Original Wuyuan Li Na and other SIFIC infection horizons　

Author: Wu Yuan Li Na Jin Wenting Ma Yuyan

Review: Hu Bijie and Pan Jue

First, a brief introduction to medical history

Male, 63 years old, from Shanghai, was admitted to the Infectious Diseases Department of Zhongshan Hospital for the second time on November 23, 2022.

Chief complaint: indwelling catheterization with repeated urine color turbidity for 2 months and then 8 days.

Current medical history:

On September 19, 2022, I went to a hospital in Shanghai for fatigue, anorexia and dysuria. WBC 10.12×10 9/L, N 87.6%, Hb 53g/L, hsCRP 135.22mg/L, ESR 62mm/H, albumin 30.1g/L, Scr 589μmol/L, K 2 were examined. Urine routine: WBC 3892/ul, occult blood 3+/RBC 5579/ul, protein 2+; Chest CT: bilateral pleural effusion, partial atelectasis of lower lobe of both lungs; Abdominal pelvic CT: Bilateral middle and upper ureteral dilatation and renal pelvis and calyceal dilatation, the patch in the right part of calyceal is slightly high density, the bladder wall is thickened, there is a little flocculent blur around the left renal fat sac and ileocecal part, and there is a little effusion in the pelvic cavity. A large amount of turbid urine was drained by indwelling catheter. Urine culture showed that Klebsiella pneumoniae was positive. Considering urinary tract infection, acute kidney injury, hypokalemia and severe anemia, patients were given symptomatic support treatment such as anti-infection, bladder irrigation, antioxidation, potassium supplementation and blood transfusion. The symptoms of patients improved and the urine was slightly clarified. 10-18 Review urine routine: WBC3+, RBC3+, protein 1+, SCR 263 μ mol/L.

I was admitted to our department on October 19, 2022. Blood routine: WBC 5.08X10 9/L, N 66.1%, inflammatory markers: ESR 19mm/H, hsCRP 52.3mg/L, PCT 0.52ng/ml, Scr 257μmol/L, and urine routine: WBC 28493/μ. Urinary color Doppler ultrasound: hydronephrosis, bilateral ureteral dilatation, bladder wall thickening significantly; Abdominal pelvic CT: hydronephrosis of both renal pelvis and ureter, thickening of ureter wall (inflammatory change), inflammatory change of bladder and ureter may be large, the volume of both kidneys increases and the substance is thin. Meropenem 1g q12h is given for empirical anti-infection. Urology consultation considers the acute stage of infection, so it is not suitable to put double J tubes. If necessary, pyelostomy can be done, but it does not improve renal function much. Bladder irrigation is recommended. 10-20 middle-stage urine culture (sampling on October 19): Klebsiella pneumoniae was positive; 10-22 urine culture drug sensitivity: Carbapenem-resistant Klebsiella pneumoniae (CRKP), adjusted to ceftazidime and abamectin 2.5g q12h for anti-infection, and daily bladder irrigation. After treatment, the urine color of the patients gradually became clear, and the urine white blood cell and bacterial count gradually decreased during follow-up. The urine bacterial culture was negative on November 1 and November 4. Check the urine routine on November 09: WBC 28/uL, RBC 4/uL, urine protein+,bacterial count 29/UL;Blood WBC 7.64×10 9/L, N 76.5%, hs-CRP 0.4mg/L, ESR 25mm/H, PCT 0.18ng/mL, Scr 175μmol/L, which were significantly improved compared with those at admission. Stop ceftazidime and abamectin on November 11 and be discharged.

On November 15, 2022, the patient appeared turbid urine again, and there was no fever and other discomfort. On November 23, he was admitted to the hospital for a second diagnosis and treatment.

Past history: In September, 1991, T12-L1 comminuted fracture was treated with internal fixation. After operation, the catheter was retained for half a year due to urinary incontinence, and then the catheter was removed after urination. There was no urinary tract infection during this period. Diabetes for 16 years, insulin therapy, blood sugar control can be; Hypertension for 5 years, oral amlodipine to reduce blood pressure, blood pressure control can be.

Second, the admission examination (admitted on November 23, 2022)

[physical examination]

T: 36.2℃ P: 90 times/min R: 20 times/min BP: 176/105 mmHg.

Stay in bed, feel refreshed and calm, lose weight, and muscle atrophy of lower limbs; Breathing sounds in both lungs are thick, and dry and wet rales are not heard; The rhythm of the heart is regular, the abdomen is soft, without tenderness and rebound pain, without mass, without percussion pain in both kidneys, without tenderness at ureter point and rib and waist point, and the lower abdomen does not touch the enlarged bladder. During indwelling catheterization, the urine in the urine collection bag is turbid and more white flocs are deposited. Limbs are not swollen.

[Laboratory examination]

Blood routine: WBC 7.85×10 9/L, N 81.3%, HB 121g/L, PLT 170×10 9/L.

Urine routine: WBC 2775/μ l; RBC 2/μl, bacterial count: 39879/μl, nitrite positive, leukocyte esterase+++.

Inflammation markers: hs-CRP 17.9mg/L, ESR 68mm/H, PCT 0.12ng/mL.

Biochemistry: ALT/AST 23/21U/L, Alb 47g/L, Scr 199μmol/L, eGFR 30ml/min/1.73m2, na/k 140/5.5mmol/l.

Third, clinical analysis

Characteristics of medical history: middle-aged and elderly male, indwelling catheter, with repeated urinary turbidity and abnormal urine routine. Urine culture showed CRKP one month ago, and it improved after ceftazidime-ababactam treatment, but urine turbidity reappeared three days after drug withdrawal, blood inflammatory index increased, urinary leukocyte and bacterial count increased significantly, and the diagnosis of urinary tract infection was clear. The reasons for short-term recurrence after antibacterial drug treatment improved were considered:

Recurrence of CRKP infection: The patient has been indwelling catheter for 2 months, and there may be biofilm formation of catheter and abnormal urinary tract structure, which makes it difficult to completely eliminate the infection and relapse after stopping taking the drug. Therefore, urine culture and drug sensitivity test can be improved.

New infection: the patient has high risk factors of recurrent urinary tract infection, and the pathogen may be different each time. The patient’s previous CRKP infection treatment was effective, and the possibility of new pathogen infection should be considered in the short term, until the urine culture is perfect and clear.

Multiple infections: patients with abnormal urinary tract structure, indwelling catheter and other risk factors can not be removed, so it is necessary to be alert to the possibility of multiple pathogens including fungi combined with infection, repeat the cultivation of urine bacteria, mycoplasma, fungi and mycobacteria, and improve urine mNGS to help clarify the infected pathogens.

Four, further examination, diagnosis and treatment process and treatment response

On November 23, 2022, the middle urine smear was used to find bacteria: moderate amount of G- bacilli, and continued ceftazidime and abamectin 2.5g q12h ivgtt for anti-infection and bladder irrigation.

On November 26, 2022, the bacterial drug sensitivity of the middle-stage urine culture (sampling on November 23) was CRKP, ≥ 100,000 /ml, and urine mNGS: a large number of Klebsiella pneumoniae (species strict sequence number: 406,866) was detected.

On November 29, 2022, the abdominal and pelvic CT was reexamined: bilateral dilated hydronephrosis accompanied with inflammatory changes of ureter, and the parenchyma of both kidneys was thin, and the inflammatory changes of cystitis might be larger, similar to that of 22-10-20 slices.

November 30, 2022 (sampling on November 29): Enterococcus faecalis was positive. On December 2, according to the drug sensitivity, fosfomycin 3g qod was added orally, and ceftazidime and abamectin were suspended.

Repeated urine cultures on March, April and June, December, 2022: Enterococcus faecalis was positive and CRKP was negative.

On December 8, 2022, the urine WBC was 38738/μ L, and the bacterial count was 43285/μ L; Urine culture: CRKP positive, Enterococcus faecalis negative.

Phage therapy was carried out from the afternoon of December August, 2022: Phage cocktail (composed of 5 strains of Klebsiella pneumoniae phages A103KP172, A106KP176, A121KP192, A49KP106 and A58KP118, 5mL each), injected with 225mL physiological saline (according to the estimated bladder volume), and the total volume was 250mL, and then the catheter was clamped.

Urine routine on the third day of phage treatment on December 11, 2022: white blood cell count: 235/uL, bacterial count: 722/uL；; Urine bacterial culture was negative.

Urine routine on the 5th day of phage therapy on December 13th, 2022: white blood cell count: 279/uL, bacterial count: 92/ul; Urine bacterial culture was negative; Blood WBC 6.35X109/L, N 70%, hs-CRP 0.9mg/L, ESR 26mm/H, and inflammatory index decreased compared with before; Re-examination of urinary color ultrasound showed that bilateral renal pelvis separation and upper ureteral dilatation were better than before (10-20), and the thickness of bladder wall was reduced (12-25mm→13mm).

He was discharged from hospital on December 14, 2022 for follow-up.

V. Final diagnosis and diagnosis basis

Final diagnosis:

Complex urinary tract infection (CRKP, Enterococcus faecalis)

Neurogenic bladder, hydronephrosis and hydroureter (indwelling catheter)

Renal insufficiency

Diagnostic basis:

The patient is a middle-aged and elderly male with neurogenic bladder caused by paraplegia, indwelling catheter, turbid urine with flocs, increased CRP and PCT, significantly increased WBC and bacterial count in urine, repeated CRKP positive in urine culture, positive in enterococcus faecalis, abdominal basin CT: hydronephrosis of renal pelvis and ureter, anti-infection, normal inflammatory markers and urine routine after phage treatment, clear urine and negative urine culture, so complicated urinary tract infection.

The patient suffered from anorexia and dysuria, and the serum creatinine increased obviously. Abdominal CT showed that both kidneys were enlarged, the cortex was thin, and bilateral urinary tract was hydronephrosis. After active treatment such as controlling infection and improving renal function, the serum creatinine decreased, so the diagnosis of renal insufficiency was clear.

Six, experience and experience

Phage is a targeted sterilization virus in nature and a sterilization star in the "pre-antibiotic era". Phage therapy has a history of more than 100 years, but the discovery and application of broad-spectrum antibiotics have gradually marginalized it. With the increasingly serious problem of bacterial drug resistance, phages have once again received attention and become the most promising supplement and alternative therapy for treating superbugs. The clinical application of phage in China is relatively late, but it has developed rapidly in recent years. In 2017, the Shanghai Institute of Phage and Drug Resistance was established, with Professor Hu Bijie as an academic member. Since 2018, the institute has carried out the first clinical trial of phage therapy in China. At present, it has treated nearly 100 patients with drug-resistant bacterial infections from all over the country and accumulated rich clinical experience in phage therapy, which is a leading position in the field of clinical phage therapy in China.

Phage has many advantages, such as host bacteria dependence, targeted specific sterilization, no infection to eukaryotic cells (little influence on normal flora), no influence on bacterial drug resistance, synergy with antibacterial drugs, penetration of biofilm and so on. The cure rate of acute bacterial infection is high, and the therapeutic effect of chronic bacterial infection is no less than that of antibacterial drugs, and the safety of phage treatment is also extremely high. A systematic retrospective study showed that the vast majority of patients who received phage therapy had no or only slight adverse reactions, 86.7% patients’ clinical symptoms improved, and 78.8% patients achieved the eradication of pathogenic bacteria. Our clinical trials also show that more than 70% of patients have achieved good therapeutic effects, and there are no obvious cases of adverse reactions. This patient was repeatedly infected with Klebsiella pneumoniae due to long-term paraplegia, abnormal urinary tract structure, indwelling catheter and other factors. The diagnosis of complicated urinary tract infection was unquestionable, and the choice of antibacterial drugs was limited due to multi-drug resistance and renal insufficiency. Phage therapy is very suitable.

The disadvantages of phage therapy include narrow host spectrum, individualized plan (it is difficult to treat empirically), no unified standard for the best treatment decision, and rapid tolerance. Phage cocktails, combined antibacterial drugs and multiple treatments are usually used in clinic to improve the curative effect. At present, the targeted pathogens of phage therapy in our team mainly include: multi-drug resistant Gram-negative bacteria (Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecalis); Covering respiratory system, urinary system, abdominal cavity, bones and joints, skin and soft tissue and other infected sites; Treatment depends on the site of infection, and intravenous application of phage is still being explored. In this case, the patient didn’t have percutaneous nephrostomy because of the little clinical benefit, so he was treated by transurethral bladder perfusion, and the phage could not cover the whole urinary tract evenly. Although the pathogen turned negative in a short period of time and was well tolerated, its long-term curative effect may not be good, and it needs repeated phage treatment.

Phage therapy has huge clinical demand and broad market. In recent years, our team has focused on the clinical application (treatment and prevention and control of nosocomial infection) and basic research of phage therapy, with a view to becoming a powerful weapon to curb drug-resistant bacteria in the future.

references

[1] Uyttebroek S, Chen B, Onsea J, Ruythooren F, Debaveye Y, Devolder D, Spriet I, Depypere M, Wagemans J, Lavigne R, Pirnay JP, Merabishvili M, De Munter P, Peetermans WE, Dupont L, Van Gerven L, Metsemakers WJ. Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review. Lancet Infect Dis. 2022 Aug; 22(8):e208-e220.

[2] Chegini Z, Khoshbayan A, Taati Moghadam M, Farahani I, Jazireian P, Shariati A. Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review. Ann Clin Microbiol Antimicrob. 2020 Sep 30; 19(1):45.

[3] Lusiak-Szelachowska M, Weber-Dabrowska B, Gorski A. Bacteriophages and Lysins in Biofilm Control[J]. Virol Sin, 2020,35(2):125-133.

Every Monday night

The Department of Infectious Diseases of Zhongshan Hospital affiliated to Fudan University in Shanghai will be with you!

Photo: Xiaoxiao

Original title: "Detective Case: The Nemesis of Super Bacteria is Coming"

Read the original text

　　BEIJING, Feb. 1 (Leng Haoyang) Today, the 40-day Spring Festival travel rush kicked off. According to China Railway Corporation, in 2017, a new line of 3,038 kilometers was put into operation, and the "four vertical and four horizontal" high-speed rail network was completed and put into operation ahead of schedule. This also means that a number of railways will meet the first Spring Festival travel rush exam. Which new railway lines will help you go home during the Spring Festival this year? Do these railway lines pass through your hometown?

　　Chongqing-Guizhou Railway: Chengdu-Chongqing Quickly "Hand in Hand" in the Pearl River Delta

　　Every year, Spring Festival travel rush, Chengdu and Chongqing are the key areas where it is difficult to grab tickets. This year, an important railway line in Spring Festival travel rush will give people in this area a more convenient choice to "go home".

　　On January 25, 2018, the Chongqing-Guiyang Railway was put into operation, which became a fast railway channel to connect Chengdu-Chongqing area and even southwest area to South China and East China, and then connected with the existing high-speed railway lines such as Guiguang, Chengdu-Chongqing and Shanghai-Kunming. A large-capacity transportation channel will help Spring Festival travel rush.

　　The Chongqing-Guiyang Railway leads from Chongqing West Railway Station, passes through Qijiang, Zunyi and Xifeng, and finally reaches Guiyang North Railway Station, with a total length of 347 kilometers. It is a double-track electrified railway with passenger and freight lines. Twelve stations, including Chongqing West, Luohuang South, Qijiangdong, Rushui East, Tongzi North, Tongzi East, Loushanguannan, Zunyi, Longkeng, Zunyi South, Xifeng and xiuwen county, have been newly built, with an initial maximum operating speed of 200 kilometers per hour.

　　At the beginning of the opening of Chongqing-Guiyang Railway, 66 pairs of passenger trains will be arranged, and the running time of Chengdu, Chongqing-Guiyang, Guangzhou, Kunming and Changsha will be greatly shortened.

　　Xicheng high-speed railway: the history of "difficult roads" has been rewritten.

　　Joining Spring Festival travel rush’s army for the first time this year is Xicheng High-speed Railway.

　　"It’s difficult to get through the Shu Road, but it’s difficult to get into the sky", which has always hindered the traffic development between the north and the south of Qinling Mountains. However, with the opening of the Xicheng high-speed railway, the history of "difficult roads" has been rewritten.

　　On December 6 last year, Xicheng high-speed railway was officially opened for operation. Xicheng high-speed railway leads from Xi ‘an, Shaanxi Province, passes through Ankang and Hanzhong in Shaanxi Province to Guangyuan and Mianyang in Sichuan Province, and connects with Mianyang-Chengdu-Leshan Railway at Jiangyou Station, reaching Chengdu, with a total length of 658 kilometers.

　　Xicheng high-speed railway operates at a speed of 250 kilometers per hour. The shortest travel time between the two places is reduced to 3 hours and 27 minutes, which is 7 hours shorter than the original shortest travel time between the two places.

　　The opening of Xicheng high-speed railway will greatly ease the pressure of Spring Festival travel rush between Xi ‘an and Chengdu. On the afternoon of January 31st, the reporter inquired about the train tickets between Xi ‘an and Chengdu on February 14th (the 29th of the twelfth lunar month) and February 21st (the 6th day of the first lunar month) through the 12306 client, and found that many high-speed trains still had tickets left.

　　Data Map: Last December 28th, with Shijiazhuang — The D1611 train from Qingdao North left Shijiazhuang Railway Station, and the Shijiazhuang-Jinan high-speed railway was opened for operation. The picture shows the first train of D1611. China News Service reporter Yujia Zhai photo

　　Shiji high-speed railway: Shanxi, Hebei and Shandong provinces realize high-speed railway connection

　　On December 28th last year, the Shijiazhuang-Jinan high-speed railway was put into operation, and there was no direct high-speed railway between the capital cities of Hebei and Shandong provinces. The last section of China’s "four verticals and four horizontals" high-speed railway network officially closed.

　　Shijiazhuang, Hebei Province and Jinan, Shandong Province are the two capital cities of Shiji High-speed Railway, with a total length of 298 kilometers. Its east and west ends are connected with Jiqing High-speed Railway and Shitaike Special Railway respectively, which enables Shandong, Hebei and Shanxi provinces to realize high-speed rail connection.

　　The line also connects with Beijing-Guangzhou high-speed railway at Shijiazhuang Station and Beijing-Shanghai high-speed railway at Dezhou East Station, with 11 stations in total. In addition to Shijiazhuang and Dezhou East Station, there are 9 new stations in Shijiazhuang East, Gaocheng South, Xinji South, Hengshui North, Jingzhou, Pingyuan East, Yucheng East, Qihe and Jinan East.

　　At present, there are plenty of tickets for Spring Festival travel rush-Shijiazhuang High-speed Railway. On 31st, the reporter found that there are plenty of tickets for the trips between the two cities from February 12th to 15th before the Spring Festival and from February 20th to 22nd after the Spring Festival.

　　Data Map: The first G2028 train of Baolan High-speed Railway will run to Xuzhou, Jiangsu, a thoroughfare city of five provinces more than 1,500 kilometers away. Yang yanmin

　　Baolan High-speed Railway: Take the High-speed Railway to the Silk Road.

　　What kind of experience is it to take the high-speed train home on the Silk Road?

　　On July 9, last year, Baolan High-speed Railway was put into operation, with a total length of 401 kilometers, with eight stations including Baoji South, Tianshui South, Qin ‘an, Tongwei, Dingxi Northwest and Lanzhou West, with an operating speed of 250 kilometers per hour. Now, from Lanzhou, you can reach Xi ‘an in 3 hours at the earliest, and it takes only 8 hours and 20 minutes to reach Beijing.

　　Baolan high-speed railway is connected with Xi ‘an-Baoji high-speed railway and Lanxin high-speed railway, which have been opened to traffic, respectively, from the east and west directions. With the opening of this "last mile", it means that from Xi ‘an, Shaanxi Province, the starting point of the ancient Silk Road, to Urumqi, Xinjiang, a "high-speed railway silk road" with a length of more than 2,300 kilometers runs through the whole line, and the northwest of China is fully integrated into the national high-speed railway network, and the high-speed railways in eastern, central and western China have achieved full interoperability.

　　Similar to Xicheng High-speed Railway and Shiji High-speed Railway, the opening of Baolan High-speed Railway also eased the pressure on Spring Festival travel rush. On the afternoon of the 31st, the reporter found that on February 13th and 14th of the pre-holiday peak, and on the 20th and 21st of the post-holiday peak, there were sufficient tickets for the high-speed rail between Xi ‘an and Lanzhou, and there were also a small number of tickets left in the business seats and first-class seats of some trains from Beijing to Lanzhou.

　　Zhanghu High-speed Railway: Inner Mongolia Entering the "High-speed Railway Era"

　　People in Inner Mongolia can also take the high-speed train home in Spring Festival travel rush this year!

　　The first new high-speed railway in Inner Mongolia, Zhanghu high-speed railway from Wulanchabu to the eastern section of Hohhot, was officially opened for operation on August 3 last year. After the opening, the running time from Hohhot to Wulanchabu was shortened to 40 minutes.

　　Zhanghu High-speed Railway (Wulanchabu to the east section of Hohhot) starts from Hohhot East Station, passes through its Yingnan Station and Zhuozi East Station, and finally reaches Wulanchabu Station, with a total length of 126 kilometers and an operating speed of 250 kilometers per hour.

　　In the future, Zhanghu high-speed railway will also be connected with the Beijing-Zhangjia high-speed railway under construction, forming a fast passenger passage from Beijing to Hohhot within 3 hours.

　　Data Map: On September 29th last year, the first train K4518 from Lanzhou to Chongqing set off, marking the opening and operation of the whole line of lanzhou-chongqing railway, which took nine years to build. Yang yanmin

　　Lanzhou-chongqing railway: The northwest and southwest are more closely linked.

　　In addition to the above-mentioned Chongqing-Guizhou Railway and Xicheng High-speed Railway, there is also a railway connecting the southwest that will help Spring Festival travel rush and facilitate people in the southwest to travel.

　　This is the grand railway passage connecting the southwest and northwest of China — — Lanzhou-chongqing railway.

　　Lanzhou-Chongqing Railway passes through Gansu, Shaanxi, Sichuan and Chongqing provinces, one city and 22 cities and counties. It is a national I-class railway with double-track electrification of passenger and cargo. The main line is 886 kilometers long, with a design speed of 160 kilometers per hour, and 200 kilometers per hour is reserved for conditional sections.

　　Nowadays, the transportation distance from Lanzhou to Chongqing has been shortened from 1,453 kilometers to 886 kilometers, and the bus running time has been shortened from 21 hours to the current 12 hours, which greatly facilitates the travel of passengers between the southwest and northwest regions.

　　Jiujing-Qu Railway: Ending the History of Many Places Closed to Traffic

　　During this year’s stay in Spring Festival travel rush, people in Poyang, Duchang, Jingdezhen and other places will have a more convenient way to go home.

　　Jiujingqu Railway was opened to traffic on December 28th last year. It is a double-track electrified express railway with a design speed of 200 kilometers per hour. It starts from jiujiang railway station, Jiangxi Province and ends at Quzhou Station, Zhejiang Province, with a total length of 333.3 kilometers.

　　Jiujingqu Railway constitutes the auxiliary connecting line of Beijing-Kowloon and Shanghai-Kunming, which connects with Hefu high-speed railway at Wuyuan Station, plays an important role in connecting east and west and connecting north and south in the road network node, and is another convenient passage for Central China and Southwest China to closely connect with the Yangtze River Delta and the southeast coast.

　　With the official operation of Jiujingqu Railway, there are no trains in Poyang and Duchang, and it has become history that Jingdezhen has no trains. (End)

Broadband access to households will improve the quality of people’s lives and create a good opportunity for the development of digital economy. The development of broadband is an urgent event in the strategic deployment of "Broadband China". In the beginning of 2021, an unusual "broadband storm" training operation and a bullish "opening the door" assault battle quietly kicked off in Hainan East.

At the beginning of 2021, the broadband development of Hainan Mobile Oriental Branch encountered a bottleneck and the progress was slow. "Can broadband coverage in the township regional grid speed up the progress?" "What if the customer needs broadband, but the port is full or uncovered?" "After broadband recording, how to solve the problem of withdrawing orders due to installation difficulties?" Faced with these difficult problems that restrict the development of broadband, the Party branch of Orient Mobile attaches great importance to it, and in accordance with the overall arrangement and requirements of the relevant work of the Party Committee of the company, and in accordance with the general instructions of "strong responsibility and high goal traction", it holds a special research meeting, plans in advance, and is determined to tackle these difficult "hard bones" and vows to fight a beautiful "tough battle" with high standards and strict requirements.

After full brewing and preparation, the "Broadband Storm" training campaign of Orient Mobile in the first season of the Spring Festival kicked off. The leaders led the team, and all the staff were on duty. For three weeks in a row, they threw themselves into this storm nonstop. The cadres took the lead in moving the "stones" and the employees Qi Li attacked the "hills". All the staff took responsibility, worked together and innovated bravely, which solved the problems of broadband development.

"The tour was carried out for 17 days, with more than 90 marketing staff, 232 natural villages, more than 500 visits to the village, more than 100,000 kilometers of driving, more than 7,900 kilometers of walking and more than 22,000 customers. The effect of the activity greatly exceeded expectations!" Fu Yong, the head of the "Broadband Storm" training campaign, made an inspiring speech at the activity summary meeting.

Get up early, get in the dark, enter the village, go to the countryside … The branch committee sets the direction, sets an example, stabilizes the morale and strengthens confidence for the training team; First-line personnel led the team to charge ahead, stationed at the training site, busy during the day, and summed up and studied the next strategy overnight; Backstage personnel stick to the rear, support the construction of broadband sites around the clock, re-record broadband withdrawal records, and release activity data; All the members walked the streets and lanes, expanding while building, installing with the sale, and never falling after the sale, and traveled all over the East …

On the third day of the operation, there were frequent explosions, and the situation was excellent! The action team decided urgently that it was not allowed to wait for a special period, and all available resources, including the internal team and the external cooperation team, must be mobilized, and the original division of labor lines and divisions should be reorganized, and the nets should be cast in groups.

The new site was shortened from 7 to 10 days to 5 days!

The installation speed is shortened from 3 days to 1 day!

Every day, the installed capacity is 3 times more than usual!

In the later period, related after-sales problems and troubleshooting can’t be left behind, and all the teams responsible for the package should go all out to do all the services in the area. Every team member bursts out of his own small universe, which will be impossible to become possible!

"Seeing this final achievement, we really didn’t even dare to think about it, and we didn’t have time to think about it. Along the way, our idea is very simple, that is, insist on persisting, and if there are not enough people, we will’ catch the strong men’. With this experience, we will not be afraid in the future. " Zhao Rihui, manager of Dongfang Mobile Jianwei Center, said.

"In this’ broadband storm’ training operation, my biggest feeling is the outbreak of team strength! The efficiency of our grid has achieved a qualitative leap! In the meantime, the leaders gave us full attention and support, and helped us solve the problems that restricted broadband marketing in the first time, so that everyone could develop their business without any worries and felt extremely warm. " Party member Zhou Liangli, the liberation grid of Dongfang Mobile, expressed such feelings.

As she said, in this unique "broadband storm" training operation, every team broke out with great strength, especially the grid members who charged in the front line, and everyone was very amazing!

17 days of struggle! 3 times the usual work efficiency, accelerating and accelerating, far exceeding the conventional tasks! Mobilize all available resources, whatever you can, and break the conventional combat mode! Blasting orders, assault, rain or shine, overcome all difficulties! During the zipper operation, Orient Mobile made a concerted effort to sprint towards the same goal, achieving extraordinary breakthroughs and promoting high-quality growth.

Let’s go down! This is the normal work of all members of Orient Mobile during the "Broadband Storm" training operation. This year’s opening storm, let us see the strong synergy of a team.

This "broadband storm" has guided all employees of Orient Mobile to stick to the initial mission of red communication, turn the "struggler" culture into productivity, and strive to be strugglers and dream catchers in the 5G era! Everyone will set up their sleeves and work hard, unswervingly move forward, reach the goal rain or shine, maintain the enthusiasm and feelings of "customers can’t wait, but we can’t wait", create new glories in the 5G era, help build Hainan Free Trade Port with practical actions, and present a gift for the 100th anniversary of the founding of the Communist Party of China (CPC).

camera lens

There is no end to serving customers.

During the storm training, the entire liberation grid team fought for 17 days in a row. At eight or nine o’clock in the evening, I was still drying orders in the group. The grid leader looks at everyone’s hard work and hard work. In addition to being moved, he is more distressed.

One weekend, I finished 20 orders in the morning, thinking that everyone had worked hard for so many days, and I planned to let everyone have a rest for the afternoon. So, the grid leader said in the group that they would have free activities in the afternoon, so everyone could take a rest and recharge their batteries. As a result, everyone replied in unison: "Don’t rest, stick to it!"

Dai Yue’s Journey on a Star

When the team members of Chengdong Grid were stationed in Jiaxi Village for marketing, they encountered a customer’s network equipment problem and could not be installed, which was very difficult. After understanding the situation, regardless of the fact that it was getting late, everyone drove 70 kilometers to Jiaxi Village with the engineering maintenance personnel and the installation master at the first time, and after checking the first-class boxes and the second-class boxes one by one, they re-pulled the cable non-stop.

Because the length of the line is 150 meters and there are many branches on the way, the whole process takes more than 4 hours … In order not to lose any customers, even if they fly to Dai Yue, even if it is late at night, they still feel full of happiness …

A different kind of "complaint"

When I went to Nadou Village to install cables for customers, the village lanes were narrow and there were too many equipments. In order to improve the installation efficiency, Jiefang Grid’s small partner rented a tricycle from a local old man, with Lin Qiong as the driver, carrying the cables and the installation master through various rural lanes.

At 9 o’clock that night, when everyone was still installing the machine at the scene, they received a "complaint" call from 10086. The owner said, "The people of the mobile company agreed to rent it for one day, but why haven’t they pulled the car back yet …"

"Hard work" warms people’s hearts

At 8 o’clock in the evening, after handling the fault complaints for a day, my body was exhausted and my stomach was rumbling. At this time, the members of the North Grid received a phone call: "Master, do you have time to come to the intersection of the vegetable market now? I will pick you up to my home improvement broadband. " The person who answered the phone replied without hesitation, "OK, now go over."

At the customer’s home, the customer not only helped to carry the box, but also quickly opened the telescopic ladder. The master climbed up with the rubber cord and the customer helped to hold the ladder. An hour later, the leather line about 150 meters long was finally pulled.

At 9: 30, when the installation was registered, there was a problem with the system, and it was too late to register. At this time, two bottles of iced green tea were handed to them: "Thanks!" The master looked at these two bottles of green tea and heard these words, and the fatigue caused by the installation of nearly two hours vanished instantly.

Look at these "beautiful" data.

Jiefang Grid: I traveled all over 73 villages in 8 towns and villages in Dongfang City, and 5 cars traveled nearly 30,000 kilometers.

East Grid: It has traveled all over 10 towns, 25 administrative villages and 10 natural villages in Dongfang City, with a total of nearly 22,000 kilometers of vehicles.

South Grid: Running all over 52 administrative villages, the vehicles have traveled more than 26,000 kilometers.

East Grid: It has traveled all over 61 administrative villages and 53 natural villages in 5 towns and villages in Dongfang City, with a cumulative vehicle travel of nearly 20,000 kilometers and an average daily marketing time of more than 10 hours.

North grid: It has traveled all over 58 administrative villages in Dongfang City, and the cumulative vehicle travel is nearly 25,000 kilometers.

250,000-350,000 yuan, for many people, this seems to be a more moderate price range. It will not lose its value, nor is it out of reach. As for pure electric vehicles, it is the trend of the times, and it is also caused by demand. Therefore, we will recommend several pure electric vehicles with 250,000-350,000 yuan to you today, and I like your dishes.

Polestar 2

High-performance electric vehicle brand, which is the brand positioning of Polestar, so we can imagine the highlight of Polestar 2-it is a pure electric vehicle with driving and control attributes, and the word "driving and control" is precisely one of the most scarce attributes of pure electric vehicles at present, which has become the reason why I recommend it. However, we will elaborate on this point later, and let’s talk about another big reason why this car makes me feel excited. Volvo Gene Blessing, to be honest, I am not surprised that Polestar 2 is presented to our simple vision, but this does not affect my good impression of it. At least it shows excellent originality and recognition while presenting simplicity, both inside and outside, and the materials are exquisite.

Three endurance versions (485/512/565km), Polestar 2 gives consumers a lot of choices, but in fact, one endurance version has only one configuration version to choose from … It is a little flawed, but fortunately this is not the point. The point is that in this era of comfort and compromise, it still insists on becoming a car that emphasizes driving sense, which is not easy. Specifically, its power output is agile. Every time you tap the accelerator pedal, the body will give you positive and direct feedback, and this sensitive and light feeling will enhance your driving confidence subconsciously. This is a pure tram that makes you easy to "get on top". Note that "get on top" here does not mean dizziness, but refers to the driving desire that will be stimulated, which is very rare.

ZEEKR 001

If we have to trace back to the source, ZEEKR 001 is related to Polestar 2 we introduced earlier, but the reasons why I recommend these two cars are not the same. Polestar 2 is because of driving control, and 001 is more because of its hunting style. There is only one product at the same price, and the scarcity is self-evident. Of course, what I mean by "scarcity" here is more about the car body structure, because 001 is really not new when it comes to design elements alone. The popularity of this design language over the years has made us lose the surprise at first sight. What needs to be reminded is that when we test-drive 001 before, it had defects such as electric door and car system stuck, so it is recommended to make a decision after the actual experience in the store.

Perhaps because of the blood relationship, even ZEEKR 001 and Polestar 2 have the same attitude towards endurance selection and configuration selection, and there are also three endurance versions (526/606/712km) to choose from, and there is only one corresponding configuration version. However, considering that the version of our test drive experience was the WE version with long endurance and driving experience, we will share it as a reference model. The acceleration of 544Ps, 768N·m and Zero Hundred takes only 3.8s s. I think these data are enough to make up part of your imagination of 001. It is fierce enough. Although its car weight is not light, its explosive power still surprises me. Coupled with the effective filtering of various bumps, the sense of movement and comfort of the whole car is very balanced.

Model 3

ZEEKR 001 and Polestar 2 are recommended to everyone because of their scarcity, but the reason for recommending Model 3 is completely opposite-it is because it sells well enough, and you can even see it in the top three of the car sales list, which is enough to explain something. After all, judging from the sales during this period, it is not an accident that it sells well. In terms of design, the impression that Model 3 presents to us is also simple, but this simplicity is completely different from Volvo-style simplicity. The latter tends to be exquisite, while the former is more inclined to be scientific and technological. It is this avant-garde that has made this design look backward for so many years. Of course, for some people, the overly simple interior may feel that it is not worth the price.

In terms of endurance version and configuration selection, Model 3 is relatively limited, with only 556/675km(CLTC). As for the actual experience, taking the high-performance version as an example, it takes time to get used to driving Model 3-you must carefully grasp the amount of accelerator pedal to ensure that you will not be frightened by the instantaneous response and instantaneous high torque performance. Of course, this also reflects its strong power from the side. In many people’s subconscious, shouldn’t pure electric vehicles be like this? Although the driving control is disliked by some loyal fans of fuel vehicles, the zero-hundred-acceleration can still make them far behind. The suspension adjustment of Model 3 is actually eccentric, but it is not so hard, just like chocolate. Moderate hardness.

I picked up the Honda Fosha 350 in April, 2011, and the current mileage is 9,600 kilometers.

Talk about my problems, modification and maintenance:

[Kneeling ]1. Idle jitter (this common problem of scooter is understandable),

[Kneeling ]2. The starting belt slips, the belt hits the box, and it is unstable, wobbly and abnormal. Appear after 3000 kilometers, the speed does not shake after coming up, and it is very smooth. Once it is lower than 20 kilometers per hour, it will often appear, especially in the initial stage.

[Kneeling ]3. The tire is not very good, the temperature does not come up, and the grip of the tire is seriously insufficient. The key point is that after 9000 kilometers, the tire is prone to puncture and leak. At present, it has leaked twice. The new tire is back and will be replaced soon. (Tires are too thin and not durable, and it is easy to cause safety hazards such as puncture, trachoma, puncture and air leakage after 9000 kilometers.) It is recommended that you replace them quickly when you drive to 10000 kilometers. It is also suggested that you install a better set of external tire pressure monitoring, the price is about 200-500 yuan. I installed it, and it really works. When the air pressure is low, it will remind us, so that we can find the air leakage in advance and go to the tire repair shop in advance.

[Kneeling ]4. The original windshield is a piece of garbage. It is too short to be practical to look at and must be replaced. I bought three windshields before I bought the right one. Recommended brands: rich GIVI, original made in Thailand, or Feitianshi. The height is suggested to be 47cm and 52cm. I bought 47 black and normal, 52 transparent and thickened, and increased the transparent color of 58 kV windshield. I have bought all these. I suggest you buy 52 thickened ones according to the actual measurement of long-distance and high-speed rotten roads. Don’t ask me why it is proved by practice. There’s …

[Like ]5. Add modified pit avoidance: In fact, add modified things:

Tire pressure monitoring, (useful)

Mobile phone holder, (useful)

Expanding rod, (depending on personal needs)

Pedal,, (depending on personal needs)

Spotlight, (not recommended, illegal, useful at night)

Brake, (depending on personal needs)

Tyre, (useful)

Guardrail, (depending on personal needs)

Headlights, (useful local tyrants can change the price to around 2000)

Support trunk, (useful and practical, long distance, many items)

Invisible car clothes, (starting in 2000 is not recommended to prevent small scratches)

Double flashing, headlights, ess, (depending on personal needs)

Shock absorption, (little effect, unsprung weight is too big)

The electric heating handle thickens the heating seat cushion (depending on regional and personal needs).

Hand guard, (it is better to wear a good glove)

Air intake and exhaust, (illegal, not to mention the noise of a single cylinder, but the performance can be improved together)

Fuel tank bag, (according to personal preference)

Backrest, (it’s expensive, isn’t it sweet to add a trunk? )

Change the transmission, (there is no good scheme at present, there are good schemes and modifications that can be changed)

Electric rearview mirror, (depending on personal needs, local tyrants are free)

Rearview mirror convex mirror, (useful)

Instrument film, (must be pasted, it is easy to scratch the instrument without pasting, which is only 15-60 yuan).

[stand hand]6. Maintenance articles ..

Prepare:

, preferably 10-30W, or 10-40W (original engine oil, G2 G3, Weishuang Raytheon Mott can be used as long as it is genuine ~)

(Honda’s original engine oil grid price is about 160, and it is recommended to use the price of 15-30 yuan has a similar effect)

Air filter, (at present, the original factory wants 90-170 yuan)

Gear oil, which is also 10 ~ 30w, is as common as engine oil, and does not need to be purchased additionally.

Transmission cleaning

Tools, masters, people with strong hands-on ability, you can trust me privately if you don’t understand the specific practice.

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The exterior design of Wuling Hongguang S3 fully reflects the perfect fusion of practicality and fashion. The front part adopts a family-style design, and the exquisite air intake grille and LED headlights set off each other, giving the vehicle a unique recognition. The body lines are smooth, the overall style is simple, atmospheric and dynamic, showing Wuling’s attention to detail. Whether it is city driving or long-distance travel, Hongguang S3 can show a good visual effect.

The side lines of the Wuling Hongguang S3 are designed smoothly, and the body size is 4655mm x 1735mm x 1790mm, showing a solid body profile. The wheelbase is 2800mm long, providing good support for the interior space. The front and rear wheel tracks are 1450mm and 1465mm respectively, ensuring driving stability and handling flexibility. The tire size is 205/65 R16, and it is matched with a delicate wheel design, which is not only practical, but also adds a fashionable atmosphere to the vehicle. Overall, the side design of the Wuling Hongguang S3 is not only practical, but also pays attention to aesthetics and details.

The interior design of Wuling Hongguang S3 focuses on practicality and comfort, and adopts warm color matching to create a spacious and bright sense of space. The steering wheel is made of plastic material, although it is not high-grade leather, it is in line with its positioning and cost-effectiveness. A simple and easy-to-use multimedia screen is integrated on the center console, which supports USB interface, which is convenient for passengers to connect mobile phones and other devices. The front row is equipped with a USB/Type-C interface to meet the charging needs of different devices. As for the seats, whether it is the main driver’s seat or the passenger’s seat, they are made of fabric material to provide a good riding experience. The seats support front and rear adjustment and backrest adjustment to ensure a personalized comfortable experience for passengers. The second row of seats is also equipped with front and rear adjustment and backrest adjustment functions to meet the passenger’s riding needs. Regarding storage space, the rear seats can be reclined as a whole, providing a flexible space solution for loading bulky items.

The Wuling Hongguang S3 is equipped with a 1.5L displacement L4 engine with a maximum power of 73 kilowatts, providing stable power support for the vehicle. In terms of torque, this engine can output 140 Nm, ensuring smooth handling of the vehicle in daily driving. Matched with a 6-speed manual transmission, it not only satisfies driving pleasure, but also takes into account practicality.

Summarizing the evaluation of the owner, although he has a supportive attitude towards its domestic identity, he also pointed out some shortcomings of the Wuling Hongguang S3. The owner believes that the vehicle has an atmospheric appearance, practical interior, and affordable price, which is suitable for various road conditions, especially mountain climbing roads. However, he expressed dissatisfaction with the clarity and computing power of the central control screen, as well as the car-machine interconnection function, and suggested that the factory make improvements. In addition, he also highlighted the issue of engine displacement and adjustment, arguing that these factors affect the driving experience. In response to this feedback, we can expect Wuling Motors to be optimized in subsequent models to meet the needs of more owners.

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The Maybach S-Class presents an unparalleled exterior design with its luxurious and noble temperament. On the front face, it uses a delicate chrome grille with elegant lines to convey a low-key sense of luxury. In overall style, the Maybach S-Class combines classic and modern, streamlined body design and meticulous carving of details to create a visual effect that coexists with dignity and technology. Every detail reflects Maybach’s insistence on quality and precise grasp of user requests.

With its elegant and unique side design, the Maybach S-Class presents an ultimate luxury temperament. The body size reaches 5470mm x 1921mm x 1510mm, and the wheelbase reaches a spacious 3396mm, resulting in a sense of space and comfort. The front and rear wheel tracks are 1655mm and 1683mm respectively, ensuring driving stability. The tire size is 255/45 R19, which not only matches the dynamic performance of the vehicle, but also presents an elegant rim style, further strengthening the identity of its luxury car series. Every detail reflects the rigorous pursuit of craftsmanship and design of the Maybach S-Class.

The interior design of Maybach S-Class is luxurious and exquisite, and it creates a luxurious atmosphere with exquisite materials and craftsmanship. The steering wheel is made of genuine leather, which is simple in design and comfortable in grip. It supports electric up and down + front and rear adjustment, so that the driver can adjust the best driving position according to personal needs. The 12.8-inch central control screen stands on the dashboard, and the clear display content and advanced automatic speech recognition control system can easily control functions such as multimedia, navigation and phone, bringing convenient and intelligent experience to the driver.

In terms of seats, the Maybach S-Class is made of high-grade leather to provide a comfortable ride experience. The front seats not only have 4-way adjustment functions, including front and rear, backrest, height and waist support, but also are equipped with heating and ventilation functions to ensure passengers’ comfortable ride in any weather. The power seat memory function can be set for the driver and co-pilot’s memory, and the rear seats also support front and rear adjustment and leg support, providing passengers with all-round luxury enjoyment. The overall interior design cleverly blends functionality and luxury, highlighting the unique charm of the Maybach S-Class as a luxury sedan.

The Maybach S-Class is equipped with a powerful 3.0T engine with a maximum power of 280 kW and a peak torque of 500 Nm, releasing 380 horsepower. This engine, combined with a sophisticated 9-speed automatic transmission, provides a smooth and efficient driving experience, ensuring the vehicle’s outstanding performance in various road conditions.

Summarizing the views of the owner of the Autohome, he deeply felt that the exterior design of the Maybach S-Class is full of domineering and business atmosphere. The unique chrome-plated and pie wheel hub design, as well as the luminous Maybach logo, are undoubtedly a symbol of identity and status. Although the new model has replaced the Maybach logo with a Mercedes-Benz logo, this does not seem to weaken the owner’s understanding and appreciation of the essence of the Maybach brand. He expressed the owner’s unique emotion for this luxury car with the sentence "Maybach L is not a logo, but a waist that has not been straightened for so many years".

On May 29, Fan Bingbing posted a photo with Li Chen on the Internet to officially disclose their relationship. According to the media, this is also the first time Fan Bingbing has taken the initiative to disclose his relationship to the public in the 18 years since his debut.

Unlike ordinary artists, Fan Ye has been in the entertainment industry for 18 years, and his love life has always been talked about. It is understood that before Li Chen, Fan Ye had more than ten reliable and unreliable "boyfriends", ranging from the 40s to the 85s.

Fan Bingbing and Wang Xuebing were photographed swimming and playing together in Hainan

Wang Xuebing: The only genuine ex-boyfriend

In 2004, Fan Bingbing and Wang Xuebing, who filmed the TV series "Top Gun Pack Qingtian", made a fake play. A year later, the two were filmed playing in an intimate water at a hotel in Sanya, Hainan, and the news of their love finally came out. At the time of the most intimate relationship, it was even reported that they lived together in Beijing and went to a family dinner together in Xinjiang. However, in 2007, this relationship came to an end. However, to this day, Wang Xuebing is still the only ex-boyfriend Fan Bingbing has ever admitted to. She once said in an interview with the media that Wang Xuebing is a very important man in her life. Although they are no longer together, they have really experienced particularly good memories. In her words: "He is the kind of man who warms my heart when I think about it now."

However, time has changed, and good fortune has tricked people. Ten years later, Fan Ye is in full swing, but Wang Xuebing’s popularity is not as good as before. On March 9 this year, Wang Xuebing was sniped by the mysterious "Chaoyang masses" in Beijing again, and was caught by the police while taking drugs in a community in Beijing. The impermanence of fate makes people sigh.

Fan Bingbing and Samuel Hung

Samuel Hung: 2 million buy a mansion for Fan Ye

On May 20, "national husband" Wang Sicong and Fan Bingbing started a war of words on Weibo. This time, Master Sicong still did not change his poisonous nature and left a message under Fan Bingbing Weibo "Jinbao Xueqi Family Seal". The implication was naturally to satirize the three bosses who had an affair with Master Fan. It was said to be the boss, maybe these three were really old.

Born in 1949, it was revealed that Hong Jinbao, a kung fu superstar, had lived with Fan Bingbing at Sanquan Apartment in Shanghai and a high-end apartment in Beijing. The whistleblower even claimed that Fan Bingbing had entered Hong Jinbao’s room after one o’clock and left after five o’clock. Even the soho modern city apartment where Fan Bingbing lived was a property that Hong Jinbao spent more than 2 million yuan to buy for Fan Bingbing. Not only did Fan Bingbing firmly deny the scandal, but Hong Jinbao was furious.

At an event, when a reporter asked "as Fan Bingbing’s godfather, have you met Fan Bingbing’s boyfriend," Mr. Hung’s reaction was quite intense: "Who is my godfather? Fan Bingbing is your godfather? Then have you met Fan Bingbing’s boyfriend? Have you met Fan Bingbing’s grandfather? Have you met Fan Bingbing’s godfather? You haven’t seen it either, so why are you asking me?"

Fan Bingbing and Wang Xueqi

Wang Xueqi: Going to court due to scandals and rumors

Another boss named by the national husband has a long history of rumors with Fan Ye. Although the two sides have repeatedly refuted the rumors, they can’t stop. In a fit of anger, the parties sued the relevant media to the court and asked them to apologize and compensate. Fan Bingbing and Wang Xueqi, although they are more than 30 years apart in age, the relevant scandals are not groundless. The two have taken on many plays, such as "Zhao’s Orphan", "October Siege" and "Rizhao Chongqing", and even in "Iron Man 3", the two joined hands to play a gorgeous soy sauce. According to Wang Xueqi, Fan Bingbing was introduced to the director of "Rizhao Chongqing" by him. He said that in fact, the role of Bingbing was not so easy to act, and he did not expect her to act so passionately. Although she seemed to be a weak woman, she was reckless when acting passionately. So a good actor is not much in the play, but whether the character can make a deep impression.

As for the news that the media reported Fan Bingbing was living with him, Wang Xueqi did not say a word and directly took the media to court. In the end, after more than a year of trial, the Chaoyang District People’s Court in Beijing ruled that Wang Xueqi won the case. The defendant newspaper must publish an apology statement to Wang Xueqi himself in a prominent position in the entertainment page within seven days after the judgment takes effect, and compensate 60,000 yuan for mental damage. Wang Xueqi said after learning the verdict: "I hope they will take their work seriously and treat others well in the future."

Fan Bingbing and Xu Jiayin attended the event

Xu Jiayin: The Innocent Real Estate Tycoon Lying Gun

With the rise of Evergrande in Chinese football, the name of real estate tycoon Xu Jiayin has also become more and more famous. However, under the disruption of Sicong, the past affair between Xu Jiayin and Fan Bingbing was exposed by netizens. In 2011, Fan Bingbing, who has been lying on the gun many times, was exposed to the news of pregnancy by the media, and this time, the father of the child became the former richest man in China. The news also caused a sensation when Xu Jiayin’s large-scale tourism project in Qingyuan, Guangdong Province was launched, Evergrande Agency had established a cooperation with institutions such as Fan Bingbing Studio to establish the largest cultural agency in China.

Fan Ye, who usually took an indifferent attitude towards his scandals, went to the police station to report the case the day after the news came out. It seemed that Boss Xu was indeed innocent.

The Man Hidden Behind Fan Bingbing

Mu Xiaoguang: The man behind Fan Ye’s success

Fan Ye’s agent, Mu Xiaoguang, is the driving force behind Taiwan’s entertainment industry and is said to be worth 1 billion yuan. After coming to the mainland to develop, he immediately fell in love with Fan Bingbing. He soon helped him break away from Huayi Brothers and established Fan Bingbing Studio himself.

In 2008, Fan Bingbing and Mu Xiaoguang were rumored to have an affair. At the time, it was rumored that the man, in addition to working hard for Fan Bingbing’s affairs, also tied a heart lock for her at the Yue Lao Temple through the Internet, and made love eggs for Yiren in the crew, which moved Fan Bingbing greatly. However, Mu Xiaoguang has always firmly denied: "I have an employment relationship with Fan Bingbing, and she hired me to help her manage her studio."

No matter what the real situation is, Mu Xiaoguang’s ability to deal with scandals is first-class. After Fan Bingbing left Huayi Brothers to fly solo, it can be said that he was entangled in negativity and had a difficult future. However, under Mu Xiaoguang’s handling, Fan Ye was unflappable. Opening a company, casting a new film, filming a new drama… Although the negative news and scolding have never stopped, Fan Bingbing’s popularity has skyrocketed all the way, and finally achieved the golden signboard of the entertainment industry, "Fan Ye".

Li Chen’s ex-girlfriends

As the saying goes, how many girls love × ×, how many × × do not cherish. Although Li Chen cannot compete with Fan Ye in his career, he is not at a disadvantage in the matter of affairs. Just after Fan Ye revealed his love affair with Li Chen, Li Chen’s ex-girlfriend Zhang Xinyu updated a Weibo saying: "The last Weibo about you: Sometimes the person you think you have been around for a lifetime may suddenly disappear, or even have no time to hug. Three years, time flies. No matter what the outside world thinks. You want to be happy! Mu Zi Yuchen." Maybe this is the real reason why Cannes and Fan Ye are torn up in blood. Everyone has to sigh that you can make your ex-girlfriend so dead-hearted. Li Chen, you are really a winner in life! ( Could it be that that stone really had such a miraculous effect back then?!)

Zhang Xinyu in Cannes

Heart-shaped stone seller Li Chen teaches you how to pick up girls

At the 2012 Qixi Festival, Li Chen revealed his love affair with Zhang Xinyu. The two showed their love all the way, and Zhang Xinyu posted the "heart-shaped stone" given by the mileage on the Internet, claiming that the stone was unique. However, netizens were not optimistic about this relationship, and Zhang Xinyu became the target of public criticism because of this. Real and fake scandals such as plastic surgery and being a lady on the stage continued to spread. In the end, Zhang and Li’s relationship soon ended in a breakup.

Just as Li Chen Zhang Xinyu was showing her affection, an ex-girlfriend was killed halfway. Dilina, a girl from Xinjiang, posted the same heart-shaped stone and said, "Did you wholesale a bunch?" For a time, netizens were full of gossip. Subsequently, many of Li Chen’s ex-girlfriends, including Liu Yun and singer Lan Qin, were found to have a heart-shaped stone in their hands.

Dilinal, who has no mercy on Li Chen, is a model for her predecessor

It is understood that Dilina, who exposed the "Stone Gate" incident, is a young model in Xinjiang. It is said that Dilina and Li Chen also appeared in a nightclub together in May 2012. It is not clear when the two broke up. However, some speculate that it should be Zhang Xinyu’s successful insertion that caused the relationship between the two to end. Dilina was ruthless to Li Chen after the breakup. She once posted on Weibo: "The nature is hard to change, this is true." Directly accusing Li Chen of hypocrisy.

Liu Yun posted a screenshot of the heart-shaped stone by netizens

"Wife" Liu Yun: I have also received Li Chen’s heart-shaped stone

After it was exposed that Li Chen gave heart-shaped stones to his current girlfriend, ex-girlfriend and mother, it was discovered by netizens that during the filming with Liu Yun in 2011, Li Chen also gave heart-shaped stones to Liu Yun. At that time, a good news user posted on Weibo: "In order not to alarm the blogger, I will not forward the picture, but send a screenshot. The blogger is Liu Yun, and when he was filming with Li Chen, he was also given a stone heart. Speechless… There are pictures and truth. In the comments, Liu Yun replied that Li Chen picked it up."

Li Chen’s move was ridiculed by netizens. Some netizens said that "collecting seven dragons can summon the dragon". Liu Yun is the wife of singer Zheng Jun and a mainland actress. She has starred in many film and television dramas such as "Son of Heaven 2", "The Red Girl of the Three Heroes of the Wind and Dust", "The Book of Deer Ding Ji" and "The New Cut Plum". She registered her marriage with singer Zheng Jun in Xi’an on May 26, 2010.

Li Chen and Li Xiaolu

Li Xiaolu: Because of the drama, he became a stranger in the end

In 2002, Li Chen and Li Xiaolu co-starred in the TV drama "Thirteen Grid" for the first time. The two fell in love because of the play, and their relationship was exposed. According to people in the circle, the relationship between Li Chen and Li Xiaolu lasted for many years, and Li Chen, who was in love, also stabbed the word "Lu" on Li Xiaolu’s thigh for Li Xiaolu. Li Chen’s relationship with Li Xiaolu was not surprising in the entertainment industry, and netizens did not pay much attention to them, but this did not affect the tacit understanding between the two.

In 2010, the media broke the news that Li Chen and Li Xiaolu broke up. In the face of the media’s bombardment, Li Chen responded to the public for the first time about his past love with Li Xiaolu. Li Chen said frankly: Not saying does not mean forgetting. Li Chen also claimed to be persistent in love and gave all his true love for Li Xiaolu. Although he was hurt by love, he never regretted it. As for the reason for their breakup, Li Chen and Li Xiaolu both said that because they were too busy with work, they had been separated for a long time, and their relationship naturally faded after a long time. What the truth ***** no longer important. Li Xiaolu married Jia Nailiang in 2012 and married as a woman. And Li Chen is also a beauty, so why bother with old love?

Since 2022, the big health trend has continued to be strong, and functional beverages have ushered in a dividend period. Nielsen data shows that in 2022, domestic functional beverage sales reached 46 billion yuan. Among them, nutritional supplements have become an important category driving the growth of the functional beverage market.

Recently, Nongfu Spring’s Vitamin Water has also launched two new flavors after seven years – prune peach flavor and grapefruit compound flavor. From the taste point of view, Vitamin Water uses the popular fruit prunes and fresh grapefruit as the fruity base in recent years, continuing the combination concept of vitamin C and vitamin B.

Industry insiders believe that it is not difficult to see from the two new flavors launched this time that Vitamin Water has been paying attention to the needs and taste trends of young people. In particular, the prune and peach flavor is very likely to lead to a new taste trend, so that near water drinks and functional drinks will be "rolled up" again.

In 2010, Nongfu Spring Power Emperor Vitamin Water was launched. Unlike later products such as charcoal and tea pi, "Vitamin Water" directly expresses the original intention of the product – hoping to help consumers meet their needs anytime and anywhere through Vitamin Water.

From today’s perspective, vitamin water is undoubtedly trendy and practical. More than a decade ago, the concept of big health was not deeply rooted in the hearts of the people, and vitamin water was still a trendy concept. However, consumers still accept and recognize the name. When it comes to "vitamin water", everyone subconsciously knows that it is a beverage under Nongfu Spring.

In 2017, Vitamin Water changed its packaging, and the bright color of the drink was matched with a capsule-like bottle design and a striking letter "V", which was very visual. The packaging style has always been based on the product itself, and the capital letter "V" represents both the product name "Vitamin" and the meaning of "Victory".

At the same time, the product concept of vitamin water has reached a consensus with consumers’ needs. Consumers can clearly know the flavors and formulas represented by different colored beverages at a glance, and quickly find what they need.

Some industry insiders have commented on the uniqueness of vitamin water. At present, functional drinks are no longer exclusive to sports and fitness enthusiasts, and this category is gradually becoming a daily lifestyle drink. And vitamin water, with its outspoken product name, bright and colorful appearance and rich taste, reduces the communication cost between functional supplement drinks and young consumer groups, and realizes personalized expression.

Vitamin Water has been named a "fashion trend" brand character by young consumers, not only because of its unique packaging design, but also because the brand has always maintained a close dialogue with young consumer groups. Since 2017, Vitamin Water has sponsored and supported a number of popular variety shows and music festivals, and has cooperated with popular movies on IP. Vitamin Water’s continuous brand cooperation is not only to take advantage of the opportunity to promote, but also to support shows or cultural products to help them realize their commercial value.

On the other hand, the continuous support of phenomenal cultural products has also made vitamin water the most trendy product under Nongfu Spring, and has also gained a large number of young fans. After 2017, vitamin water has become a super single product in the functional beverage category.

As a drink that has stood with young people since its birth, Vitamin Water not only cares about their preferences but also their needs. In recent years, "smooth intestines" has become the focus of young people’s attention, which is also the original intention of Vitamin Water to launch the first prune-flavored water drink on the market. For the industry, this is very likely to lead to a new taste trend. For consumers, this is another conversation between Vitamin Water and them.

Fast Technology news on June 21, according to the official release of Li Auto,The new L6 launched in 64 days to deliver super 30,000 units…

Interestingly, it is also today, ask the official announcement of the new M7 Ultra listing 20 days will be more than 30,000 units, the current delivery has been more than 10,000 units, although the price of the two cars is different, but there is indeed competition, choose the same day to send a battle report, it can be seen that there is quite a bit of acupuncture, vowing to fight for male and female meaning.

On the 8th of this month, Ideal said that the delivery of the new L6 has reached 20,000 units, 13 days have passed since today, and now 10,000 units have been delivered.Average daily delivery of 770 vehiclesThis achievement is indeed quite outstanding.

The Ideal L6 is positioned as a family luxury five-seat SUV and is the smallest and cheapest model in the Ideal family. The car is only available in two configurations, Pro and Max.The whole series is equipped with four-wheel drive, and the price range is 24.98-27 9,800.

All 8295 car machine chips, Nappa leather seats, two rows of four seats heated and ventilated massage, front double seats 10-point massage, front double seat memory, comes with five seats and 5 soft pillows, double-layer laminated sound insulation glass, huge panoramic sunroof (with sunshade), Max high ratio and low matching, more with lidar high-end smart car, platinum audio and rear compressor refrigerator.

In terms of power system, the ideal L6 is fully equipped with a 1.5T range extender + front and rear dual motors, with a maximum system power of 300 kW, a peak torque of 529 Nm, a zero-hundred acceleration of 5.4 seconds, and a top speed of 180 km/h (electronic speed limit).

Built-in 36.8 kWh lithium iron phosphate battery and a 60-liter large-capacity fuel tank,CLTC operating conditions pure electric battery life 212 kilometers, comprehensive operating conditions 1390 kilometersThe battery supports fast charging, which can be charged from 20% to 80% in 20 minutes.

Since its launch, Ideal L6 has quickly become the best-selling domestic new energy SUV in the 250,000 class, and has also become Ideal’s most popular brand model and sales support this year.