February 4th is the 17th World Cancer Day, and this year’s theme is "WE CAN, I CAN". The member of the Standing Committee of Cancer Radiotherapy Committee of China Anti-Cancer Association and the president of Cancer Hospital said: At present, 70% of cancer patients in our city are in the middle and late stage when they are diagnosed, so it may be a better choice for them to eliminate the fear of cancer and realize coexistence with cancer.

　　70% of cancer patients need to live with tumors.

　　Mr. Luo, who lives in Yubei District, is 55 years old. He is used to working from nine to five every day. If no one tells him, no one will think that he is actually a cancer patient. Five years ago, he suddenly felt that he was always urinating, but he couldn’t urinate. At first, he thought he was getting angry. But a pile of heat-clearing drugs didn’t improve after eating, and the more urgent the urine, the less smooth it was, and sometimes it was accompanied by pain. At this time, he thought about going to the hospital for examination.

　　I didn’t want to be diagnosed with prostate cancer and have bone metastasis. I have lost the best opportunity for surgery and can only use antiandrogen drugs to control my condition. In the face of cancer, he did not intend to give up, but actively cooperated with the treatment. After one year, his condition gradually stabilized, and Mr. Luo began to plan to go to work in the unit.

　　Professor Dean of the Municipal Cancer Hospital said that according to the "2015 China Cancer Statistics" issued by the National Cancer Center, there were 4.3 million new cancer cases in China in 2015, and the number of cancer deaths exceeded 2.8 million; In Chongqing, there were about 80,000 new tumors and more than 50,000 cancer deaths in 2014. Because the incidence of tumor is relatively concealed, more than 70% of cancers are found in the middle and late stages, and the best opportunity for surgical treatment is lost. For them, survival with tumor may be a better choice.

　　Unfortunately, in real life, there are not many patients who can scientifically understand the survival with tumors like Mr. Luo. As soon as many patients heard that they could not operate, their spirits suddenly collapsed and they thought they were hopeless. In fact, surgical treatment is not the only treatment for all tumors; Even if we miss the best opportunity for surgical treatment, it doesn’t mean that there is no cure. At present, tumor treatment advocates comprehensive treatment, which includes surgery, chemotherapy, radiotherapy, endocrine therapy, traditional Chinese medicine treatment and other ways. Experienced specialists will choose the appropriate treatment according to the results of tumor pathological examination, course of disease and development trend.

　　"It is very important for cancer patients and their families to accept" survival with tumor ",which is a more pragmatic method for treating advanced cancer." Dean said that cancer is essentially a genetic disease, and all cancers come from genetic mutation, which is caused by genetic mutation and epigenetic regulation. At present, human beings can’t use drugs to reverse this genetic mutation and "kill all cancer cells" in the body.

　　It is also a pragmatic choice for patients in the middle and late stage to realize long-term "survival with tumor" and "peaceful coexistence" with tumor. Everyone should treat it as a medical disease with disease, and treat tumor as a chronic disease such as hypertension, diabetes and coronary heart disease, which is more conducive to treatment.

　　The misunderstanding of survival with tumor needs to be vigilant

　　There may be many people who don’t understand that living with a tumor is not cured. There is a tumor in the body, and the condition may deteriorate at any time. Can this be safe? Dean Wu Yongzhong said that in fact, survival with tumor is not to let it go, but to choose a suitable treatment model, which is also the core of "individual medicine" developed from "evidence-based medicine" in recent years. First of all, we should recognize the fact that the dream of conquering tumor has not been realized.

　　WHO has regarded tumor as a chronic disease, because its condition has a process of development, which can not be cured and exists for life, just like diabetes, hypertension and coronary heart disease. Secondly, sometimes over-active treatment is also a kind of injury. In clinic, some elderly cancer patients are often encountered. When children hear that they can have surgery and treat at all costs, they have not achieved good results. This is because the elderly, especially those over 80 years old, have degraded their physical functions and cannot tolerate surgery and chemotherapy at all.

　　At this time, you don’t have to think about eliminating the tumor at all. You can choose radiotherapy alone or other treatments, so as to survive with cancer. Advocating survival with tumor again also means waiting for treatment conservatively. If it can be cured by surgical resection, radiotherapy and other treatment methods, tumor patients should still be encouraged to actively treat.

　　Age-related macular degeneration (AMD) mostly occurs in people over the age of 50, and it is one of the main blinding diseases of the elderly in the world. According to statistics in 2010, there are more than 23 million AMD patients worldwide. The patient’s chief complaint is decreased vision, which is characterized by the absence of central visual field (see schematic diagram).

　　Normal visual field (left), central visual field damage caused by AMD (right)

　　Age-related macular degeneration can be divided into Dry AMD and Wet AMD. Dry amd is characterized by no vascular proliferation, while wet amd is characterized by obvious vascular proliferation in macular area. There is almost no treatment for dry age-related macular degeneration, while wet age-related macular degeneration is mainly aimed at vascular proliferation. For vascular proliferation, Genentech’s Ranibizumab (trade name: Lucentis) is a fragment antibody against VEGFA, and it costs two thousand dollars for a shot. However, many places bypass Ranibizumab and choose Avastin (Avastin), which is also anti-VEGF, for only fifty dollars. It can be seen that there are policies and countermeasures, which are available to people at all times and all over the world, but the interests are accelerating. In addition, laser therapy is also aimed at vascular proliferation. Although there is symptomatic treatment for vascular hyperplasia, it is also a temporary solution, because macular degeneration itself has not improved.

　　A core problem of macular degeneration is degeneration of retinal pigment epithelial cells (RPE). These cells are close to the interlayer between Choroid and optic nerve cells in retina, and are responsible for bringing blood nutrition to optic nerve cells. If this layer of cells degenerates, the optic nerve cells will not get nutrition, so the vision will decrease. There’s an old saying in China, what can I do without fur? Is the image explanation of this disease.

　　A remarkable pathological feature of macular degeneration is yellow sediment distributed on the retina, which is a mixture of protein and lipid, but its source is unknown, and it may be an inflammatory product, and its pathological function is to destroy retinal pigment epithelial cells (RPE). See the figure below.

　　Since it is a degenerative disease, the research and development of drugs lacks molecular targets, which are a bit like Alzheimer’s disease and neurodegeneration, and there are not many effective targets. In contrast, the stem cell technology that surfaced in the past ten years is an ideal choice. Stem cells are induced to differentiate into retinal pigment epithelial cells (RPE), which provides a feasible and effective method for the treatment of macular degeneration.

　　Can normal retina replace diseased retina? A few decades ago, someone replaced the diseased retina with the baby’s retina (of course, the source was the baby who died in a car accident under two years old), and the success rate was very low, because the source of newborn retina was difficult, the protection was difficult, and the operation was difficult, which were all restrictive factors. However, some people have gained some vision (such as light perception and figure) through retinal replacement. This scheme can at least prove that infant retinal replacement is a direction that can be improved. However, it is not successful to replace the bad eye retina with the good eye retina of the same adult, which shows that the physiological age of retina is an important reason. Nowadays, retinal pigment epithelial cells (RPE) can be produced from stem cells, whether from embryonic sources (hESC) or from self-induced sources (iPSC), and they can be made into Sheet, which is beneficial to surgical implantation. Of course, there are many technical problems, mainly the problem of eye surgery and the problem of ensuring the survival of cells after implantation. A positive factor is that the eye is an immune escape, so don’t use immunosuppressants, immune rejection should be small, which is conducive to survival.

　　Regenerative medicine is a new field, and big pharmaceutical companies are unwilling to take this risk. Seven years ago, the author worked in the world’s largest ophthalmic pharmaceutical company (Allergan) and once recommended this project, but the decision makers are interested in Miu Miu. At present, several small companies have pushed the application of regenerative medicine in senile macular degeneration into the clinical stage. Although I dare not predict when it will be approved by the FDA, it is still expected as a promising direction. After all, there is no other way at present. Although the experiment of regenerative medicine is still in the "primary stage of socialism", the AMD market is very large, and there are still some large and medium-sized pharmaceutical companies to follow up. Not long ago, Astra, the second largest pharmaceutical company in Japan, bought Ocata Therapeutics LLC to jointly develop this method for treating AMD, which mainly focuses on hESC inducing retinal pigment epithelial cells (RPE).

　　Regenerative medicine is not only dedicated to age-related degenerative macular degeneration (AMD), but also can be used to treat another cause of blindness, Retinal pigmentosa. It also damages retinal pigment epithelial cells (RPE), but retinal pigment degeneration damages peripheral visual field, and other eye diseases such as glaucoma and corneal burn. In order to give you a big picture of regenerative medicine in treating ophthalmic diseases, the author summarizes the general situation of some companies entering clinical trials at present. I sincerely hope that these companies can succeed in regenerative medicine and bring good news to patients with ophthalmic diseases.

　　Table 1. Summary of Clinical Trials of Regenerative Medicine in Treating Ophthalmic Diseases

1905 movie network news The brand-new drag racing action blockbuster (Baby Driver), produced by British WorkingTitle and directed by British genius director edgar wright, has been continuously praised since it landed in mainland cinemas. The word-of-mouth rating of the film on authoritative rating websites such as Time and Douban ranked first in the same period, and it was also praised by domestic authoritative media, film critics, KOL and other parties. Peach trees, poisonous Sir, independent fish, etc. are even more rare "three consecutive pushes", constantly giving Amway this film to the audience: "Cool! What a leg shake! Entertainment commercial films can also be made with personality and good looks. ""The anti-routine is full of creativity, and it is difficult to find the same kind when looking around the film history! "

As a typical British director, edgar wright is well-known for his wild imagination and personal interest in smuggling illicit goods. This new work "The God of Car Theft", which has been prepared for many years, has brought his dual attributes of "fans" and "fans" to the extreme. Under his carefully selected 30 leg-shaking BGM, he not only filmed the action scenes such as racing, parkour and gun battles, but also "hidden".

Let’s take a deep look at what "stalks" in the film are worth remembering:

[Salute/Line Stud]

1. Long-shot tribute to the previous work

Shortly after the opening of the film, the long shot of "Baby" buying coffee for gang members just pays tribute to director edgar wright’s own film "Shaun the Zombie". In "Shaun the Zombie", there is also a similar long opening shot, which shows the walking corpse of Shaun, the protagonist played by simon pegg, who goes to the supermarket to buy drinks.

2&3. My ears don’t work, so I bought the wrong mask.

In the second gang robbery in the movie, Brother Dao said at the meeting that he wanted to buy the mask of Michael Myers, the killer in the Moonlight Panic series. As a result, the pronunciation of "Michael" and "Mike" was confusing, and finally he bought the mask of Mike Myers, the main actor, which became a funny stalk and appeared in the scene where gangs spit on each other before the robbery.

4&5, and "Aunt Mei" are all supporting roles … …

In the movie, "Baby" and his adoptive father sat on the sofa and watched TV at night. When they changed channels, Meryl Streep, Brad Pitt and Disney’s Monster Company 2 appeared on TV. Moreover, these movie lines that flashed on TV also appeared in the following plot.

In other words, the "baby" is learning and using the movie lines that have appeared on TV. For example, in Monster Company 2, "We are a team, and nothing is more important than our friendship." This is what "Baby" said when she was threatened by Doug on a date with Deborah and had to compromise. Besides, the sentence "These children grow up so fast!" in "Love is Complicated" "Baby" took Brother Dao’s son to seek information at the post office, and the counter staff asked him how old his child was.

6. Fight Club — — Don’t let Buddy see blood.

When changing channels, Pete’s Fight Club appeared twice before and after, and Buddy also recited the lines of Fight Club when he first saw JD’s hat tattoo: "Will this work?" In fact, it indicates that Buddy’s ending will be blackened by love, suggesting that the baby and Buddy will finally fight to death.

Director edgar wright talked about the egg in an interview: "I heard that the matador had to stand on the ground to end the battle, so the’ baby’ had to get off at last." At the restaurant, Darlene also said to the bat, "Don’t let Buddy see red, or he will get out of hand." It also implies the egg of bullfighting. Director Edgar also pointed out that "when he finally tried to kill the baby, he was immersed in the red light."

7. Pay tribute to "Desperate Mandarin Duck"

The images of "Baby" and Deborah, Buddy and Darlene in the film all pay tribute to the classic "Bonnie and Clyde": Buddy and Darlene kill each other with heavy machine guns in the film; "Baby" and Deborah are trying to escape from the world. But at the end, "Baby" didn’t run away with Deborah, but chose the right path, creating a sunny and positive ending, instead of ending in tragedy like Buddy and Darlene’s "Bonnie and Clyde".

8. "Suspects don’t need to" pay tribute to Quentin

The film also pays tribute to the plot of Quentin’s "Reservoir Dogs", and the combination of people involved in the task changes every time. In "Auto Thief", director Edgar made three robberies in order to reflect this point, each time it was a brand-new combination of people, and the third time was definitely the most wonderful super combination.

9. Pay tribute to the release day

The director has mentioned many times that the movie The Driver, which was released on July 28th, 1978, was one of the sources of inspiration for Auto Thief. The release date of "Tiger’s Mouth Pulling Teeth" appeared twice in the film: once in the long shot of "baby" buying coffee, the release date was graffiti on the street wall; The other time was the number on the clothes of "Baby" after he went to prison (2871978). Because the director was British, he put the date before the month, not the American 7281978.

10. Pay tribute to the expression of sunglasses

In the film, the "baby" bowed his head to hold sunglasses and looked up to pay tribute to Kubrick’s clockwork orange. "Head down, eyes up, I call it Kubrick lens. Every time I want to shoot, I always say to Ansel: "clockwork orange" expression! " Director Edgar revealed in an interview.　

11. "The car is heavy enough to overturn the police car!"

At the gang meeting before the second robbery, "Bat" once questioned that the "baby" wearing headphones was not listening to Brother Dao at all, and then "baby" told the whole process without breathing. One of them said, "The car must be heavy enough in case the police car needs to be overturned." This is reflected in the final life-and-death confrontation with Buddy. The "baby" directly knocked over the police car stolen by Buddy.

[Musical Feelings Terrier]

12. Why is the hero called "baby"? Why is the movie called "Baby Driver"?

Director edgar wright has explained on many occasions that generally in criminal gangs, in order to hide their identity, everyone is commensurate with the code name, and "baby" is the youngest one in the gang, so this code name is more appropriate.

The selection of the classic lyric B-A-B-Y from the hit record Carla released by "Memphis Soul Queen" in 1966 as the chat material for "Baby" and "Deborah" also echoes this setting. Interested viewers will also find that "Baby" really picked up the vinyl record of this album. The real name "Miles" of "baby" is in harmony with his identity as an escape driver. As for the title "baby driver", it is a classic single of the same name from the famous folk group Simon&Garfunkel.

13. The 15-year origin of "shaking your legs for six minutes"

The most talked about in "Car Thief" is "shaking your legs for six minutes" at the beginning of the film. But in fact, as early as 15 years ago, director edgar wright tried this creative trick to direct MV for MintRoyale, an electronic band from Manchester, England. This song is called "Blue Song" and included in the band’s 2007 album "Pop is… "in. This MV, like Auto Thief, tells the story of robbing a bank. In this MV, Noel Fielding, a British comedian, plays a No.2 driver who loves music as much as "Baby".

14. "The King of Soul Songs" Jamie Foxx teased his friend Barbara.

Bartz, the crazy shit-stirring stick in the gang, is played by Jamie Foxx, the Oscar winner and musician. In the film of 2004, he perfectly restored ray charles, the father of American soul music, with a fake performance and called him the Oscar in one fell swoop. As an outstanding musician, he has been nominated for Grammy Awards many times.

Interestingly, although "Bartz" played by Jamie in "Car Thief" is dressed as a hip-hop musician, he pretends not to know who Barbra Streisand is — — And this "award-winning professional" who has many authoritative awards such as Oscar, Tony Award, Grammy Award, Emmy Award and Golden Globe Award is actually a good friend with Jamie in private.

15. It’s unlucky to listen to Knocking on the Door of Heaven before robbery … …

"Bartz" said of his former teammate: "We were safe, but he hung up because he was listening to Knockin’On Heaven. "Make the audience laugh. This song comes from Bob Dylan, a famous American folk singer. Yes, it is the one who won the Nobel Prize last year and almost didn’t receive it.

And the phrase "Bartz" is not groundless — — Edgar wright, the director, specially interviewed real robbers for filming this film and asked them what songs they would listen to before the "action". Besides this song, there are The End of the Road and Hotel California that can’t be listened to. Interestingly, one of the robbers named Joe Loya also made a guest appearance as a robbed bodyguard in the film.

[Friendship Guest Stud]

16. Jon Spencer started and finished.

At the beginning of the film, the music of the "shake your legs for six minutes" racing scene comes from Jon Spencer Blues Disclosure’s "Bellbuttoms". The last line (not narration) before the end of the whole film is also from the lead singer Jon Spencer.

Yes, he is the one who said to the "baby", "Here’s a letter for you, boy!" The prison guard. The director said that he hoped to finish what he started, so he chose this song and wanted to end it with his voice.

17. red hot chili peppers legendary bassist "Brother Flea" has been addicted to drama again.

Eddie in the second wave of robbery gangs in the film doesn’t have much time to play, but he actually plays a lot. He is the legendary bass player "Flea" in red hot chili peppers. In addition to being a musician, he also likes to guest play some small roles in movies, such as Needles in the series and Jake, the thinking worker in the series. Coincidentally, there is also a character named "Doc" in the first part of Back to the Future, and "Griff" in the second part, which just corresponds to the code names of Kevin Spacey and jon bernthal in Auto Thief.

18. Baby’s mother is really a singer.

The most sensational of "Auto Thief" OST is "Easy". Besides the original version of Lionel Richie (yes, the one who sang "Say You, Say Me"), the film also included a cover version of American female singer Sky Ferreira. In the film, her version of the tape is not only regarded as a relic of the "baby" mother, but also played the "baby" mother herself.

19&20, these guys shouted Banana! The "underworld" is actually a musician.

The leader of the short white arms dealer (black policeman) who was killed by Bartz was played by the famous film musician paul williams. He has been nominated for the best original song at the Academy Awards for many times, and in 1977, he won both an Oscar and a Grammy for the theme song of his lyrics "Evergreen". Coincidentally, the singer and composer of this award-winning work is barbra streisand, whom Jamie Foxx "teased" in "Car Thief".

Besides, when Brother Dao met Baby in a fancy restaurant, the two gangsters around him were also famous hip-hop musicians, namely Big Boi and Killer Mike. The two have released a single together, and the former is a member of Outkast, a famous Atlanta hip-hop group, and one of the creators of Chase Me, the theme song of Auto Thief.

21, "adoptive father" seiyuu turned out to be the director’s idol.

The actor named "Baby" adoptive father is C.J. Jones. He is the first African-American deaf-mute comedian to play a movie on the big screen in Hollywood. He is really deaf-mute, and he also uses real sign language when playing. Many viewers were moved by their father and son’s previous affection.

As mentioned above, The Driver is one of the sources of inspiration for this film. In addition to paying tribute to the release date of the film, Edgar even wanted to let the film director walter hill play a role directly, but unfortunately it was not done because of the schedule. However, in the final trial scene of the film, the legendary director gave his voice by translating for the "baby" adoptive father and acted as the "seiyuu" of the second adoptive father.

22. The "Haier Brothers" in Atlanta came out again.

When the "baby" shot and wounded Buddy in the restaurant, he escaped with Deborah and hijacked a red sports car. The two young people in the sports car who were hip-hop in America were online celebrity twins, who were famous in the United States. The "yellow and violent" brothers often appeared in movies, magazine covers and the most popular MV of traprapper.

[There is no one who controls obsessive-compulsive disorder in this detail … … 】

23. The lyrics go over a wall, and spades turn into hearts in seconds.

On the way of "Baby" buying coffee and dancing, every lyric of BGM’s Harlem Shuffle appeared in various forms where he passed by. The graffiti on the background wall was originally a spade, but after the "baby" saw his favorite sister, the spade immediately turned into a heart. According to foreign media reports, this graffiti was specially drawn by the director who hired local artist Peter Ferrari.

24, listening to songs must be put from the beginning, sunglasses just can’t be taken off.

The image of "baby" sunglasses and headphones is not only cool, but also many people want to isolate themselves from the outside world.The shadow of the world’s urban civilization. For example, be sure to put the songs in the iPod from the beginning, and step on it well before driving; For example, if sunglasses are knocked out, they should be replaced immediately. The setting of sunglasses and headphones just reveals his obsessive-compulsive paranoia in his heart, and sometimes shows a little black humor, which is probably one of the reasons why the director can be sought after by fans all over the world.

25. There is a story behind the robbers’ tattoos.

If you look closely, you will find that the tattoos on the necks of several criminals in the gang and their character characteristics can always form interesting ones.Correspondence. For example, "her" and "his" tattooed by "Bonnie and Clyde" Buddy and Darlene respectively imply their inseparable love relationship; For example, Bartz really has several "bats" tattooed on his neck; For example, Lanny Joon, a Korean-born actor, initially tattooed a grandiose "HATE" (hatred). In order to expand business, the letter "E" was forcibly erased and changed to "HAT" (hat), but in fact "JD" (John Doe) means "Anonymous" in English, and this role soon got a lunch.

[which cars have the protagonist aura? 】

In the whole film, at least 34 different models of cars can be seen. The most interesting thing is that because the director specially interviewed the real robbers before, he knew that the cars they used to commit crimes would never be luxury cars like those in "Speed and Passion", but family cars with low visibility and superior performance, such as Subaru Xiaohong, the favorite car of "Baby", and Escalade, Yukon and Chevrolet Avalanche. The luxury car in the heroine Deborah’s heart is a retro classic car.

26. Subaru second-generation impreza WRX

The highlight of the film is the coquettish and domineering red Subaru in the opening six minutes. But before shooting, thisThe Subaru was changed from a full-time four-wheel drive to a rear-wheel drive, and the extremely difficult U-Turn and the continuous drift of more than 180 degrees in the film were completed. The basin friends who love cars should not blindly imitate it!

27, the second generation Chevrolet K5 Blazer

At the end of the film, "Crash Wars", "Baby" drives a second-generation K5 Blazer and Buddy produced in 1980s.Dodge Charger police cars fought each other, and finally Buddy’s car was pushed off the patio.

28, 1959 Chevrolet ImpalaConvertible.

Deborah’s ideal "luxury car" is such an old guy from the 1950s, which shows that this girl is still very tasteful. At the end of the film, as soon as the "baby" released on bail walked out of the prison gate, it was a good ending to see a beautiful woman and a beautiful car greeted him.

29. User-made GTA5 video God restores "shake your legs for six minutes"

The opening "Shake Your Legs for Six Minutes" of "Car Thief" attracted the attention of many grand theft auto v players. A foreign player named Domestic Mango on Youtube also used this game to make another 4-minute and 37-second short film, which accurately restored the most important scene of diversion, drift and sudden braking in the six-minute paragraph, and made a sincere tribute to this brand-new blockbuster that paid tribute to many classic blockbusters.

[Atlanta Real Landmark Test]

The whole film was filmed in Atlanta in the eastern United States. In order to show more realism, the director added many local landmarks and brands, and the details were embarrassing.

30. "Criminal Records"

When "Baby" first heard Deborah humming "B-A-B-Y" in the restaurant, she immediately bought the record and went home to sing and dance happily. The place where the "baby" in the film buys records is this old-school vinyl record store named Criminal Records in Atlanta, USA.

31. Bacchanalia Restaurant.

Opened in 1993, it is one of the most acclaimed high-end restaurants in Atlanta. In the film, Darlene and Buddy mentioned this restaurant when they kissed in the elevator, and then in the laundry room, "Baby" also invited Deborah to this restaurant for a date, calling it "the best place to drink and eat in the city."

32. Sweet Auburn apartment of "Baby"

The apartment where the fictional "baby" lives in the movie is actually located in the historic district of Sweet Auburn, which is near the historical site of Martin Luther King, and was once an important political, economic and cultural center for African Americans in the first half of the 20th century. We can imagine what the "baby" who lives here does every day. Maybe he will visit the town market here, where there are the best meat products in Atlanta, bakeries, bookstores, pharmacies and the most popular restaurants in 11 cities.

33. Octane Coffee

Before every important meeting of the robbery gang, "Baby" always goes to this store to buy coffee. The name "Octane" is perfect for a fast-paced car chase movie.

34. Goodfellas Pizza

When "Baby" tried to get rid of his life as a runaway driver who robbed a bank, he began to work as a delivery boy at Goodfellas Pizza, hoping to bring joy to others with his own fast driving skills.

35. Romantic road trip to the extreme: ROUTE 66 (Route 66)

Deborah described this passage when she first met Baby: "I want to drive a vintage luxury car that I can’t afford, and there is no destination all the way west, only music and roads." What a romantic thought (mood). My little sister should be an old driver, too.
　

On the wall of the restaurant where Deborah works, the most famous brand of route 66 in the United States hangs. This most famous "Mother Road" has witnessed American history since the first half of the 20th century, from Chicago across the land of the United States to Los Angeles, and it is also the location for movies such as movies and movies.
　

In fact, before the British director wrote the script, he gave himself a trip to road trip across the United States. He drove from new york to L.A. by himself, and I believe he also incorporated many special feelings in his journey at that time. Therefore, at the end of the "anti-climax" of the movie, the pair of desperate mandarin ducks staged a romantic elopement. They may really want to drive this scenic avenue from Highway 20, but unfortunately it still backfired. After Baby was arrested, Deborah mailed him a postcard, including a mural from Bo’s Diner in route 66. In the end, on the day when Baby was released from prison, Deborah was driving a vintage car. Perhaps this road trip symbolizing freedom and dreams will finally begin.

Isn’t it romantic? There are too many connotations to see? Edgar wright, the director, ingeniously combined music with racing and the anti-type and anti-routine of action elements. How can you enjoy it with two brushes and three brushes? "Auto Thief" is being shown in China. If you miss it, your summer will be incomplete!

1905 movie network news On the afternoon of August 15th, the media meeting of the International Awards Committee of Tiantan Award, the main competition unit of the 12th Beijing International Film Festival, was held in Beijing. The chairman of the award Committee attended with,, and British directors.

Asked about the criteria for judging good works and performances, several judges expressed their opinions. Amanda bluntly said that actors’ performances and directors’ creations never need to cater to the market deliberately. "That may be the producer’s business.". As an actress, what she values most is whether she is sincere enough about the roles and characters, and to do this requires enough accumulation and understanding of herself.

Wu Jing

Frant Gwo and Jason Wu also said that the purpose of being invited to be the judges of the Beijing International Film Festival Tiantan Prize is to learn more, on the one hand, from a professional perspective, on the other hand, to turn themselves into audiences and look for good works that capture their emotions.

Li Xuejian, Chairman of the Committee, was the most popular and concerned guest of the day. He bluntly said that he was very surprised and grateful for the support of the audience for decades. Li Xuejian summarized the key to being an actor as personality, artistic products and works. He will always use this as a standard to demand himself and live up to the audience.

At the same moment of the meeting, the crew officially announced that Li Xuejian had joined. Li Xuejian said that it was because of a director like Frant Gwo that he chose to participate. He also completed the performance with the encouragement of the other party, and firmly believed that he would continue to perform until he could not move.

At the meeting, Jason Wu broke the news that he had not been paid for his second participation in the series. The original huge production and epidemic situation caused Frant Gwo to overspend this time. Frant Gwo not only thanked Jason Wu for his contribution, but also promised to pay the box office.

Next, the "Tiantan Award" will continue to be judged and the results will be announced on the night of the closing ceremony in Beijing International Film Festival.

In the luxury camp of the automobile industry, Audi has always occupied a place with its unique design and excellent performance. With the wonderful appearance of the new generation Audi A5L, we can see another bold attempt of Audi in the luxury mid-size car market. This is not only a simple product update, but also a profound insight and accurate layout of Audi’s luxury car market in the future.

Let’s start with the design.

The new Audi A5L inherits the design language of Audi family, but on this basis, it pays more attention to showing the sense of movement, and at the same time, it also presents the characteristics of youthfulness.

The front face of the car adopts a more sporty honeycomb air intake net, and the long and narrow matrix lights on both sides make the whole car look more aggressive.

The embellishment of the side of the car body, semi-hidden door handles and red brake calipers not only enhances the sense of technology, but also adds a sporty atmosphere.

The design of the frameless door is a highlight of the coupe, which is beautiful and full of movement.

In terms of size, the length of the new Audi A5L has increased to 4902mm and the wheelbase has been extended to 2,965 mm.. Compared with competing products, it has obvious advantages. After such changes, the new Audi A5L is more conspicuous in the length of the car body and the internal space, bringing passengers a more spacious and comfortable feeling.

This size not only leads in data, but also brings consumers a great luxury experience in sense.

In the rear part, the new car has been upgraded to a penetrating taillight group. The application of the second generation digital OLED technology provides 8 kinds of personalized signature light signs, and the display effect is fantastic.

In terms of interiors, the new Audi A5L also spared no effort. The floating curved double screen, the entertainment screen on the front side of the co-driver, and the brand-new double-flat-bottomed touch steering wheel all make the sports elements burst. The decoration of black piano paint further enhances the texture of the car. In terms of intelligent driving, the new car matches the L2++ level unmanned intelligent driving assistance system, which shows Audi’s in-depth exploration in the field of intelligence.

In terms of power, the new A5L is equipped with the fifth-generation EA8882.0TFSI engine, and comes standard with a 48V light mixing system, which is divided into high and low power adjustment versions, and is also equipped with a quattro four-wheel drive system. This power combination not only ensures the smoothness of daily driving, but also satisfies consumers’ pursuit of driving pleasure.

The new Audi A5L is officially unveiled. It is the successor and the new strategy of Audi brand in the field of luxury medium-sized cars. This car strives to attract consumers’ attention through more luxurious configuration, more spacious and comfortable space and more advanced technology. For young users, this car is likely to become their first choice, mainly because of its unique design, outstanding brand influence and strong product strength.

Generally speaking, the new Audi A5L has added new advantages for Audi to compete in the luxury mid-size car market with its unique design, exquisite interior, strong power and leading technology configuration. It shows Audi’s profound understanding of the future luxury car market, and also embodies the brand’s spirit of pursuing innovation and breakthrough. After the official listing in 2025, the new Audi A5L will become an important highlight of the luxury car market. With these characteristics, the new Audi A5L has emerged in the market and consolidated the brand image of Audi. With excellent design concept and advanced technology, this model will surely attract the attention of many consumers. At the same time, Audi continues to invest in R&D and innovation to ensure that each model can meet or even exceed customer expectations. Therefore, when the new Audi A5L is unveiled in 2025, it will undoubtedly become a bright star in the luxury car field.

Palm oil, as one of the most important edible oils in the world, is influenced by many factors. These factors include not only supply and demand, production cost, but also international trade policy, climate change and market sentiment.

First of all, the relationship between supply and demand is the core factor that determines the value of palm oil. The main producers of palm oil include Indonesia and Malaysia, which account for most of the world’s total output. When the output of these countries increases, the supply on the market also increases, which may lead to a decline in prices. On the contrary, if the output decreases, such as due to natural disasters or decreased planting area, the decrease in supply will push up the price.

Secondly, the production cost is also an important factor affecting the value of palm oil. The production cost of palm oil includes planting, harvesting, processing and transportation. For example, the increase in the prices of fertilizers and pesticides will increase the cost of planting, while the increase in labor costs will affect the harvesting and processing links. The increase in these costs will eventually be reflected in the price of palm oil.

International trade policy also has a profound impact on the value of palm oil. Governments may influence the import and export of palm oil through tariffs, quotas or other trade barriers. For example, if a major consumer imposes a high tariff on palm oil, it will increase the import cost and thus push up the domestic price. On the contrary, if the policy encourages imports, prices may fall.

Climate change is also a factor that cannot be ignored. Palm oil production is highly dependent on suitable climatic conditions. Drought, flood or other extreme weather events may have a negative impact on the growth of palm trees, thus reducing production. For example, El Nino phenomenon may lead to drought in Southeast Asia, which will further affect the output and price of palm oil.

Market sentiment and investor expectations will also affect the value of palm oil. Speculation in the futures market and investors’ expectations of the future supply and demand will have short-term fluctuations in prices. For example, if the market expects tight supply in the future, investors may buy palm oil futures in large quantities, thus pushing up the price.

In order to show the influence of these factors on palm oil value more clearly, the following table lists the factors and their possible influence directions:

To sum up, the value formation of palm oil is a complex process, involving multiple interacting variables. It is very important for investors and market participants to understand these factors and their interrelationships, which will help them make more informed decisions in the futures market.

[Disclaimer] This article only represents the author’s own views and has nothing to do with Hexun. Hexun.com is neutral about the statements and opinions in this article, and does not provide any express or implied guarantee for the accuracy, reliability or completeness of the contents. Readers are requested for reference only, and please take full responsibility. Email: news_center@staff.hexun.com.

What I want to introduce to you today is. Let’s take a look at its performance.

First of all, from the appearance point of view, the Mercedes-Benz GLE looks hard as a whole, the grille adopts a big mouth shape, which looks very young and fashionable. With sharp headlights, it is in line with the "taste" of young consumers. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, automatic steering, delayed closing, etc. To the side of the car, the body size of the car is 4927MM*2018MM*1782MM, the car adopts avant-garde lines, the body looks very round, with large-sized thick-walled tires, the overall visual effect is very simple. In the rear design, the overall shape of the rear of the car echoes the front face, the tail lights are very dynamic, and the unique exhaust pipe creates a good atmosphere.

Coming into the car, the Mercedes-Benz GLE interior adopts a spiritual shape, and the visual effect is very good. The appearance of the steering wheel of the car looks very good, equipped with electric up and down + front and rear adjustment, steering wheel memory, steering wheel heating and other functions, and the feel is good. Let’s take a look at the central control, decorated with a 12.3-inch central control screen, which makes the interior style impressive and looks very rustic. The interior feels good. Let’s take a look at the dashboard and seats. The dashboard of the car presents a sharp design style and a sense of technology. The car adopts imitation leather seats, which are well wrapped in seats and have good overall comfort.

The car is equipped with vehicle to everything, driving mode selection, remote control key, rear wipers, interior ambient lights and other configurations. The configuration is not bad, and there is no problem in meeting daily use.

This level of models is usually the first choice for most people. First of all, the price is not expensive, and secondly, all the configurations are quite complete, which is still worth buying. If you like it, you can pay more attention!

On September 23rd, BYD officially released its new compact SUV – Sea Lion 05 DM-i, priced from 112,800 yuan, as one of the representative works of BYD Ocean Network, Sea Lion 05 DM-i adopts the fifth generation DM hybrid technology, and absorbs and elements in the appearance and interior design, forming a unique family style. The launch of this car not only enriched BYD’s product line in the entry-level SUV market, but also attracted widespread attention in the market.

?exterior design

The exterior design of the Sea Lion 05 DM-i inherits the BYD family style, the front face adopts the shape of "waves ripple", the wide bezel-less net is combined with the headlights, and the side of the body presents a streamlined design. The suspended roof is matched with metal decorative strips. In addition, the rear part adopts a through tail light design, which increases the overall design sense of hierarchy.

The dimensions of the vehicle are 4710mm (length) x 1880mm (width) x 1720mm (height), with a wheelbase of 2712mm.

?Interior design

In terms of interior, the Sea Lion 05 DM-i also continues the design concept of "marine aesthetics", equipped with a 15.6-inch adaptive rotating floating center control screen and an 8.8-inch LCD instrument panel. The ambient lights in the car offer 31 color options, creating a youthful and energetic atmosphere.

In terms of comfort configuration, the Sea Lion 05 DM-i provides multi-speed independently adjustable seat heating and ventilation functions, and the rear seats are also equipped with independent headrests. In addition, the storage space in the trunk is well-designed to accommodate various items in the family’s daily car.

In addition to the basic configuration, the Sea Lion 05 DM-i comes standard with external rearview mirror heating, electric adjustment, and other practical functions. The high-end model is also equipped with an L2-level intelligent driver assistance system, which provides adaptive cruise, collision warning and other functions.

?Power System

The Haishi 05 DM-i is equipped with BYD’s fifth-generation DM hybrid technology. The power system consists of a 1.5L naturally aspirated engine and an electric motor, with a maximum power of 120kW. In terms of fuel consumption, this car also performs very well. Under NEDC conditions, the fuel consumption is as low as 3.79L/100km, and the comprehensive cruising range can reach 1400km.

In addition, the Sea Lion 05 DM-i also offers a variety of drive modes, including EV pure electric, HEV series, HEV parallel and engine direct drive, allowing users to choose according to their driving needs.

?Intelligent Technology

In terms of intelligent technology, the Sea Lion 05 DM-i is equipped with the DiLink intelligent network system, providing a wealth of in-vehicle applications and services. The DiPilot intelligent driving assistance system equipped in the car integrates multiple functions such as intelligent navigation, forward collision warning, and blind spot monitoring.

In addition, the vehicle also supports a variety of unlocking methods, including the mobile phone NFC car key, and the external discharge function (VTOL mobile power station) allows users to power the device during outdoor activities.

summarize

The launch of the Sea Lion 05 DM-i comes at a time of intense competition in the entry-level SUV market. As a sister model of BYD, it shares the platform and technology with the second-generation Song Pro DM-i, and its positioning is very close. The Sea Lion 05 DM-i is directly competitive with competitors such as Changan UNI-Z PHEV and Dongfeng Fengshen L7 PHEV in terms of price.

The "two-car strategy" implemented by BYD in recent years has further deepened in this market segment. By launching a sister model on the same platform as the second-generation Song Pro DM-i, the Sea Lion 05 DM-i has formed effective competitive pressure in the market, which not only stimulates internal competition, but also enhances the brand’s recognition in the hearts of consumers.

?

　　BEIJING, July 5 (Xinhua) Last night, the reality show "China Star Power" of Shandong Satellite TV officially met with the audience. In the premiere program, three star tutors, Wang Jie, Wei Wei and Yang Yuying, cooperated with each other tactfully, and their comments had their own characteristics. In particular, Yang Yuying’s gentle style was unique among many poisonous comments on entertainment, and the music and dance talents fully displayed by star trainees such as Hu Yanglin and Zhu Zhiwen, as well as trainees from all walks of life at home and abroad, were really eye-catching and amazing: the era of making stars was crazy.

　　The star tutor quips that the three collided with each other and sparks flew.

　　Wang Jie, Wei Wei and Yang Yuying are all superstars who have influenced generations. They not only won the love of many audiences as singers, but also left many popular songs. The three divas, who are both singers, cooperated quite tacitly in the first program. Wang Jie’s rational judgment and the relatively emotional comments of two female tutors, Wei Wei and Yang Yuying, brought out the best in each other. However, sometimes, due to different opinions or for competing for excellent trainees, it is inevitable that there will be a dispute between words and tongues, and many sparks will collide.

　　Wang Jie, because of her frank personality, always fires at the trainees first, and then leaves the final decision to Wei Wei and Yang Yuying. At this time, the two female tutors will play the role of firefighters to put out the fire first and then clean up the mess. For example, the adapted song "Princess" brought by Yuan Jie and Chu Xiaobo, because of its novel style and unique singing method, Wang Jie first affirmed it, but then mercilessly pointed out that the pronunciation part had the obvious feeling of "pretending to be a foreign accent", and said that it was his most annoying way to deal with the sound. Yang Yuying, who was on the side, couldn’t help crying out for the contestants. She changed her gentle style and quickly argued: "This kind of singing belongs to the standard Beijing dialect, so how can we learn from foreigners?". Wei Wei, who once maintained a neutral attitude, suddenly interjected, "Jiege wants them to change into Jiege’s accent". When Yang Yuying saw someone to have them, he continued to fight back, "Jiege, you can’t mislead others like this". Without showing weakness, Wang Jie said "I have no characteristics" in a foreign accent, and Yang Yuying was so angry that he couldn’t answer the words.

　　Hu Yanglin came to Wang Jie sick and didn’t know the "big coat brother"

　　In the first program of China Star Power, the audience saw some familiar faces, including the singer Hu Yanglin, who was famous for a song "Poisonous Perfume", and Zhu Zhiwen, who was famous for his unique coat style. Although before the broadcast of the program, many questions were raised about the purpose of the two participants: "Is it unfair for such competitors who are not in a heavyweight to be on the same stage?" But the two have won the respect of star tutors and audiences with their sincerity and sincerity.

　　Hu Yanglin, who was bent on abandoning the symbol "Poisonous Perfume", chose an original song "Our Story" instead of singing a well-known famous song. Although it was a bit risky, it was affirmed by Wang Jie. Wei Wei and Yang Yuying heard that Hu Yanglin had just finished the operation and came to participate in the program. They did not agree with her disregard for her health, but Hu Yanglin sincerely explained that "I hope there is one more possibility in life, and I especially want to win this opportunity". Wei Wei and Yang Yuying were very moved after hearing this, and said that they have always liked her very much, hoping to recover well and see a better future.

　　On the dark stage, the lights suddenly lit up, so Zhu Zhiwen, the "big coat brother", appeared in everyone’s line of sight. The three tutors were really dazed, especially Wang Jie didn’t expect this to be the famous "big coat brother". Yang Yuying repeatedly questioned whether this was a guest invited by the program group. Wei Wei, who is also a fellow villager in Shandong, strongly supports it, saying that "it must be passed".

　　For Hu Yanglin’s return to the stage in this way, most of the audience expressed their support, and some netizens said that they would look forward to her next song "Perfume Lily". As for the appearance of Big Brother, although some viewers think that this is Shandong Satellite TV using Shandong native stars to make a show, they are more inclined to understand and support it. Although Populus euphratica and Da Yi Ge have different results, their devotion and love for singing is worthy of our respect and admiration.

　　Mentors and fans are talented, and alternative sissies make people "unbearable"

　　The first program of "China Star Power" under the banner of "Shaping Future Idol Stars" has all kinds of handsome guys and beautiful women, all of whom are talented and have great singing skills. Shortly after the opening, Chen Hong from Yibin, Sichuan, impressed the instructors with a song "Love the Dust". The voice was gentle and clean and had its own characteristics, so Wang Jie couldn’t help but grab the trainee. Wen Kui, who claimed to be a die-hard fan of Yang Yuying, brought an idol classic "I don’t want to talk about it", which, although adapted, was very popular with the tutor. In order not to offend the other two mentors, Wen Kui also sang two songs, "Annie" and "Asian Heroes", paying tribute to the three superstar idols when he was a child. Before stepping down, he also deliberately said that he brought his mobile phone to the stage and wanted to take a photo with his idol Yang Yuying, while Wang Jie and Wei Wei were full of jealousy and hurriedly shouted "Next, next …" Finally, the lucky fan trainee not only passed unanimously, but also took a photo with the three judges one by one, which really envied others!

　　Of course, there are absolutely no shortage of other wonderful players in the reality show column of "China Star Power". A trainee who claimed to be Echo was asked by Wang Jie if he had studied dance as soon as he came to power. Sure enough, Echo was a ballet dancer. Wei Wei praised Wang Jie for his good eye, and at the same time he was full of expectations for the trainee who stood straight and had a dance foundation. Who knows that a song "I can’t stand birds" instantly crushed the three views of three tutors, making everyone laugh and shout "I can’t stand birds". Echo’s humorous movements and tone will definitely make the audience think that this is "China Comedian Power".

On March 8th, BYD plug-in hybrid vehicle, Qin PLUS (parameter picture) DM-i went on the market, and four configurations were launched, with the subsidized price of 105,800-145,800 yuan. Whether it is the fuel consumption of 3.8 liters, the cruising range of 1245 kilometers, or the wheelbase of 2718mm that meets the standard of Didi, it can become the new favorite of the online car market.

Price subversion goes straight into the mainstream range of fuel cars

This time, the pricing of Qin PLUS DM-i has completely subverted the user’s price perception of plug-in models. In the past, there was a big price difference between plug-in and hybrid models and fuel cars of the same class, and the two markets were relatively independent. This time, Qin PLUS DM-i went straight into the mainstream price range of fuel cars, and the market boundary no longer existed. Coupled with the five major gifts launched simultaneously, BYD is full of sincerity.

Compared with the fuel vehicle of the same class, the BYD DM-i super hybrid system carried by Qin PLUS DM-i takes Xiaoyun-plug-in special 1.5L high-efficiency engine, EHS electric hybrid system and DM-i super hybrid special blade battery as the core, and even in the state of power loss, the fuel consumption of Qin PLUS DM-i can be as low as 3.8L per 100 kilometers, only over 20 cents per kilometer. In the state of full oil and electricity, the comprehensive cruising range of the 55KM version can reach 1180 km, and the 120KM version can reach 1245 km.

The design of Qin PLUS DM-i follows the Dragon Face family design language. The large mouth air intake grille is full of atmosphere, and the sharp headlights are not fashionable. The interior still uses the screen size to support the overall atmosphere. Although the LCD screen size of the dashboard is only one nainai, look at the starting price of 100,000. What kind of bicycle do you want?

BYD has never lost its sense of science and technology, such as DiLink 3.0 intelligent network connection system, cloud service, remote driving, NFC car keys, OTA remote upgrade of the whole vehicle, mobile power station and other technological configurations.

In terms of safety, Qin PLUS DM-i is equipped with DM-i super hybrid special blade battery, and adopts the world’s first pulse self-heating and the world’s leading refrigerant direct cooling technology to achieve long life and reliable safety, which relieves a big worry for new energy users.

Coupled with more than 20 intelligent driving assistance functions such as ACC-S&G stop-and-go full-speed adaptive cruise system, CSC curve speed control system, LKS active lane keeping system, LDWS lane departure warning system, AEB-CCR automatic emergency braking system, the safety can be described as very comprehensive.

With the price in the early 100,000 s, low fuel consumption, long battery life, good appearance, decent interior and, most importantly, the green license plate, Qin PLUS DM-i believe that the protagonist will become the network car you hit. What I have to spit out is that BYD’s product naming method is too complicated and lacks recognition. It is suggested to simplify the sorting again and at least reduce some confusing English abbreviations.

Speaking of pickup truck models, I believe most people will think of Ford F-150 (parameter picture), while domestic pickup trucks are mostly positioned as agricultural vehicles. Until the appearance of the Great Wall Cannon, everyone changed the impression that domestic pickup trucks are low-end and simple. Recently, we have obtained a set of spy photos of the interior of the off-road version of the Great Wall Gun from relevant channels. Compared with the ordinary version, the interior of the new car has changed greatly.

As can be seen from the picture, the center console of the new car adopts a very straight line design, so the full LCD instrument is also different from the traditional model. In the middle, there is an embedded central control panel, and the air conditioning outlet is located below the central control panel, and some silver physical buttons are retained, which is equally exquisite. In addition, it can be seen that the new car adopts an irregular gear handle design, and there are two knobs around it, one of which should be the driving mode knob.

Then let’s review the appearance. As can be seen from the previous declaration, the whole shape of the new car has a very strong American pickup style. In addition to a large number of black kits, the front of the new car also has a large area of chrome-plated material, so it is both wild and exquisite.

In the power part, the new car will be equipped with a 2.0T gasoline turbocharged engine of the Great Wall GW4C20B model, with a maximum power of 221 HP (165 kW). As for the specific four-wheel drive structure, we will announce it as soon as there is news.