Past lives of coronavirus

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This is the 2329th article of Da Yi Xiao Hu.

Up to now, there have been three epidemic outbreaks caused by coronavirus in this century, namely, Severe Acute Respiratory Syndrome (SARS) in 2002-2003, Middle East Respiratory Syndrome (MERS) that began to spread in 2012, and novel coronavirus (COVID-19) that appeared at the end of 2019. China is a country with severe disasters in SARS and this time in novel coronavirus.

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First, what is coronavirus?

Coronavirus exists widely in nature. Coronavirus was first isolated from chickens in 1930s, and it was isolated from human nasal wash more than 20 years later by scholars and named B814 virus. Later, scholars made an in-depth study of the virus from its morphology, and found that the envelope of the virus had a spinous process like a corona and a king’s crown, so the coronavirus was named from this. Its natural hosts are mainly vertebrates, and people, cows, pigs, cats and bats are all its natural hosts.

Coronavirus is slightly spherical in shape, with a diameter of 80-160nm. The "crown" on its surface is a fiber process of 12-24nm, and the end of the fiber process is also spherical. The envelope of the virus consists of two layers of lipids, with membrane protein M and fibrillary protein S interspersed between them, and some coronaviruses also have hemagglutinin glycoprotein HE. The interior of the virus is composed of RNA and nucleocapsid protein N, showing a spiral structure.

S protein is the key protein of coronavirus-infected cells, which contains host cell receptor recognition sites and is the main determinant of virus virulence. M protein is the main protein responsible for virus particle assembly. N protein is closely combined with viral RNA, which can protect viral genomic RNA through spiral stacking and encapsulation. At the same time, it can delay the growth of infected cells and make them stay in the division period for a longer time, so that viral RNA can be translated to the greatest extent. HE protein plays a key role in the formation of virus particles.

As far as virus classification is concerned, coronavirus belongs to single-strand positive-strand RNA virus, which indicates that the genetic information of coronavirus is carried by RNA, and the cloned progeny virus has a high mutation rate. After entering the host cell, it directly uses ribosomes in the host cell to produce protein needed for virus replication without transcription. Coronavirus can kill cells, thus damaging various organs, and persistent infection occurs simultaneously with acute infection, mainly attacking gastrointestinal tract, respiratory tract and nervous system.

Second, the coronavirus that humans have fought.

Before SARS, it was thought that only two kinds of coronaviruses could cause human infection. At present, there are seven kinds of coronaviruses that can infect humans, including highly lethal coronaviruses, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and novel coronavirus virus (COVID-19).

The common feature of coronavirus is that it is generally sensitive to heat, and it is moderately stable in a suitable maintenance solution at 4℃, and can be stored for several years at -60℃. With the increase of temperature, the virus resistance decreases. Coronavirus is acid-resistant and alkali-resistant, and sensitive to organic solvents and disinfectants such as alcohol and ether.

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The symptoms of coronavirus infection are mostly similar, mainly fever, chills, cough and so on. The main routes of transmission are droplet transmission and contact transmission.

1. SARS coronavirus (SARS-CoV)

Severe acute respiratory syndrome (SARS) was caused by SARS-CoV. By July 2003, it had spread to 24 provinces, autonomous regions, municipalities directly under the Central Government and 28 other countries in China. A total of 8096 clinically diagnosed cases were reported worldwide, and 774 cases died. Nearly 20%~30% of the patients needed mechanical ventilation due to respiratory failure, and the mortality rate was 9.6%. Epidemiology in many provinces and cities showed that the mortality rate increased with age, mostly over 60 years old. Its incubation period is within 2 weeks, usually 2~10 days. The population is generally susceptible and has a strong epidemic degree. The main onset age is 20-30 years old. The source hosts may be bats and civets. The transmission routes are mainly from person to person: droplet transmission in close respiratory tract, aerosol transmission and hand-to-hand contact transmission; Animals and people: civets/bats ~ people (possible). SARS-CoV has the general characteristics of coronavirus, but it is not a mutant of other known coronaviruses, nor is it a recombinant of known coronaviruses. SARS-CoV infects lung epithelial cells, and its S protein binds to angiotensin converting enzyme 2(hACE2) receptor, which invades and replicates in vivo. Because hACE2 is mainly in the lower respiratory tract, the symptoms of the upper respiratory tract are lacking, and the virus often peaks when hospitalized, which is easy to cause nosocomial infection of the lower respiratory tract.

2. MERS coronavirus (MERS-CoV)

Middle East Respiratory Syndrome (MERS) was caused by MERS-CoV, which was first confirmed in Saudi Arabia in 2012, affecting 27 countries and regions around the world, with a mortality rate of about 35%. According to statistics of a case, the mortality rate increases with age. The mortality rate is 39% in people younger than 50 years old and 75% in people over 60 years old. The longest incubation period is 14 days, and the population is generally susceptible. The median age of onset is 49 years old. Source host: it may be camel or bat. Transmission route: animal and human: dromedary ~ human (possible); People: Close contact. The infection site is epithelial cells in the lung, which causes explosive nosocomial transmission, and has obvious gastrointestinal symptoms and renal failure. It mainly binds to dipeptidyl peptidase 4(DPP4) in the lower respiratory tract, gastrointestinal tract and kidney, and there is no mutation that enhances human infection.

3. 2019 novel coronavirus (2019-nCOV)

Novel coronavirus was caused by 2019-nCOV. From mid-December 2019 to the beginning of 2020, 59 cases of unexplained pneumonia were reported in Wuhan, and similar cases were found in other regions and countries. On January 7, 2020, it was initially identified as "novel coronavirus", and on January 12, the WHO named the virus 2019-nCoV. Up to now, more than 70,000 cases have been diagnosed, and more than 2,400 cases have died, with a mortality rate of about 3.1%. It has spread to most provinces and cities in China and nearly 30 countries. The transmission routes may be droplet transmission, contact transmission and aerosol transmission. The incubation period is 1~14 days. At present, the source host may be a bat. Shi Zhengli’s team from Wuhan Institute of Virology has found that its genome is 79.5% identical to SARS-CoV and 40% similar to MERS-CoV. 2019-nCOV, like SARS-CoV, invaded by combining with human angiotensin converting enzyme 2(hACE2), infecting respiratory system, gastrointestinal tract and testis, affecting heart function and liver function. According to the current data, compared with SARS and MERS, it is more contagious and the mortality rate is not as high as the first two.

Third, actively protect against novel coronavirus

Personal protection requires frequent hand washing and hand hygiene. Cover your mouth and nose with paper towels when coughing or sneezing, which can effectively prevent the spread of droplets. Wear masks in public places, avoid contact with animals with unknown health conditions, and reduce the trading of live birds and wild animals.

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At present, various industries have started to return to work. For the office, everyone should actively declare their health. If there are suspicious symptoms such as fever, fatigue and cough, it is recommended to seek medical advice in time, avoid going to work sick, strengthen ventilation and ventilation in public areas, clean and disinfect public areas and public goods regularly, keep the environment clean and hygienic, keep a proper distance when there are many people in the unified office area, and reduce centralized meetings by video and teleconference.

Authors: Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine

Written by Zhang Yijie

Xiong xudong revises

Some pictures are taken from the network. If there is any infringement, please inform and delete them.

From tomorrow, these new rules will affect your life.

  CCTV News:Tomorrow will be August 1st, and a batch of new laws and regulations will be formally implemented. Among them, banks will cancel six charges, civil drones will be punished for not registering their real names before the end of the month, and some roads in Beijing will be closed to foreign cars &hellip all day; … For details, please see ↓ ↓

  The bank cancelled a number of charges.

  A few days ago, the National Development and Reform Commission and the China Banking Regulatory Commission jointly issued a notice, canceling the handling fee for personal cash withdrawal at the counter of the bank in different places, and suspending the collection of six fees for promissory notes and bills of exchange, loss reporting fee and production cost. All commercial banks should take the initiative to waive the account management fee and annual fee for the only account opened by customers in the bank.

  Previously, some banks would only provide customers with an account free of account management fees and annual fees if they actively applied.

  Failure to register drones before the end of August will be considered illegal.

  The Regulations on the Administration of Registration of Civil Unmanned Aerial Vehicles in real-name registration system issued by the Airworthiness Certification Department of the Civil Aviation Administration of China clearly stipulates that the owners of civil unmanned aerial vehicles must register their real names from June 1, 2017. After August 31, 2017, if the owner of the civil drone fails to implement real-name registration and paste the registration mark in accordance with these regulations, his behavior will be regarded as an illegal act in violation of laws and regulations, and the use of his drone will be affected, and the regulatory authorities will impose penalties in accordance with relevant regulations.

  This regulation applies to civil unmanned aerial vehicles with a maximum takeoff weight of 250g or more in People’s Republic of China (PRC).

  Standardize statistical investigation activities from the source

  The Regulations on the Implementation of the Statistics Law of the People’s Republic of China shall come into force on August 1, 2017. The regulations involve consolidating the responsibility of preventing and punishing statistical fraud, reducing the burden of statistical investigation objects as much as possible, strictly demanding the formulation of statistical investigation items, clarifying the procedures, conditions and time limits for the approval and filing of statistical investigation items, and clarifying the status of national statistical standards.

  New methods to improve the efficiency of patent examination

  The Measures for the Administration of Patent Priority Examination shall come into force on August 1, 2017. This method expands the application scope of patent priority examination, shortens the examination period, simplifies the examination procedures, and is expected to greatly improve the examination efficiency.

  Pesticide operators should meet many conditions.

  The Measures for the Administration of Pesticide Business License shall come into force on August 1, 2017.

  The measures stipulate that pesticide operators should meet the following conditions: they have a technical secondary school degree or above in agronomy, plant protection, pesticides and other related majors or more than 56 hours of study experience in professional education and training institutions, are familiar with pesticide management regulations, master professional knowledge of pesticides and pest control, and can guide operators who use pesticides safely and reasonably; Having a business place of not less than 30 square meters and a storage place of not less than 50 square meters, and being effectively isolated from other commodities, living areas and drinking water sources; Those who run other agricultural inputs concurrently should have relatively independent pesticide management areas.

  Beijing: Some roads will be closed to foreign cars all day.

  The Beijing Municipal Traffic Management Bureau issued a notice, in order to ensure the traffic safety and smoothness of urban roads, from August 14th, other provinces, districts and cities were prohibited from issuing license plates (including temporary license plates) for passenger cars.

  Compared with before, this traffic management measure cancelled the ban on certain sections from 6: 00 to 22: 00, and will be closed all day.

  Specific measures are as follows:Second Ring Road main road (full line), Chang ‘an Street and the extension line between Xinxing Bridge (excluding) and guomao bridge (excluding), East Square Road, West Square Road, Beichizi Street, Wang Hongbin Street, Beiheyan Street, Nanheyan Street, Fuyou Street, Beichang Street, Nanchang Street, Renmin Hall West Road, Zhengyi Road, Taijichang Street, Xi ‘anmen Street (from Xisi South Street to May 4th Street (from Beichizi Street to Donghuangchenggen North Street), Di ‘anmen Inner Street, Jingshan Back Street, Jingshan West Street, Jingshan East Street and Xishiku West Branch (from Xishiku Street to Xi ‘anmen Street) are prohibited from passing passenger cars with license plates (including temporary license plates) issued by other provinces, autonomous regions and municipalities.

Notice on matters related to the qualification review, adjustment and interview of civil servants employed in the 2024 annual examination of organs at all levels in Beijing

  According to the work arrangement for the recruitment of civil servants in the 2024 annual examination of organs at all levels in Beijing, the written test results have been announced, and qualification review, adjustment and interview will be carried out. The relevant matters are hereby notified as follows:

  I. Qualification review and matters needing attention

  The qualification review time is from January 8 to January 11, 2024, and it is conducted in the form of online review.

  (a) to participate in the qualification review must provide materials

  Candidates who enter the scope of qualification review shall provide the registration form, notice of results, ID card and electronic photos of the original relevant grades, qualifications and qualification certificates required by the qualifications of the positions they apply for, and the municipal recruitment agencies and district-level civil servants’ competent departments shall conduct online qualification review according to the qualification requirements announced in the recruitment brochure. The specific arrangement of online qualification review shall be notified by the recruitment agency by telephone, or see the website of the recruitment agency for details. In addition to the above materials, candidates must also provide the following materials:

  1. Candidates who apply for the position of fresh graduates in 2024 must provide electronic photos of students’ ID cards, graduate employment recommendation forms stamped by the department in charge of employment of university graduates and other materials. Graduates who have obtained "three good students", "outstanding student cadres" or "outstanding student scholarships" at or above the school level during their highest academic qualifications in ordinary universities outside Beijing are also required to provide electronic photos of their award certificates. Beijing Shengyuan candidates studying in foreign universities must also provide photos of their household registration book (card) in electronic version.

  Returned overseas students who obtained a degree from January 1, 2023 to July 31, 2024 must provide electronic photos of the original household registration book (if the candidate is a collective household registration book, the electronic photos of the first page of the household registration book), the electronic photos of the Certificate of Foreign Academic Degrees issued by the Study Abroad Service Center of the Ministry of Education, and the electronic photos of passports, entry and exit records issued by the public security organs and other materials for those who are not permanent residents in Beijing.

  Those who have no work experience before participating in the grassroots service projects in this city and apply for the position of fresh graduates in 2024 within 2 years after the service expires and pass the examination must provide the electronic photos of the original hukou (if the candidates are collective hukou, they also need to provide the electronic photos of the homepage of the hukou) and the electronic photos of the service certificate of "three supports and one support" for college graduates.

  2. Candidates who apply for the position of "Minimum Years in grassroots work experience" for more than two years (including two years) must provide the original electronic photos of the household registration book (if the candidates are collective accounts, they must also provide the electronic photos of the first page of the household registration book) and provide electronic photos of relevant materials that can explain their work experience and years.

  3. Candidates who apply for the position of "grassroots work experience Minimum Years" as "Unlimited" and meet the requirements for recruiting new graduates in 2024 shall provide the materials listed in paragraph 1 of this article; If you have a permanent residence in Beijing, you must provide an electronic photo of the original account book (if the candidate is a collective account, you must also provide an electronic photo of the first page of the account book).

  4. Candidates who apply for the post of retired college student soldier and the position for the disabled should not only provide the electronic photos of relevant materials according to the minimum age requirement of grassroots work experience for the position they apply for, but also provide the proof of military experience and the electronic photos of "People’s Republic of China (PRC) Disabled Card" corresponding to the type of disability required by the position.

  5. Candidates who apply for the positions of rural revitalization assistants and other service grassroots project personnel shall provide relevant materials such as employment contracts in addition to electronic photos according to the requirements of the positions they apply for.

  (2) Matters needing attention

  1. As a result of the unqualified qualification review, the vacancy of the interviewer will be notified by the recruitment agency to fill in the position in the order from high to low according to the scores of the qualified scores;

  2. Please ask candidates to keep the contact number provided at the time of registration open to ensure that they can participate in the online qualification review on time;

  3. The electronic photo image of the qualification review materials provided by the candidates should be clear and identifiable, and the photo file name should be consistent with the content of the materials. The materials that have been provided in the registration process do not need to be provided during the qualification review;

  4. If the electronic photos of some materials cannot be provided for the qualification review temporarily, candidates can communicate with the recruitment agency and provide them separately at the appointed time, but it should not be later than the end time of physical examination and inspection.

  Second, determine the first batch of interview candidates

  According to the online qualification review of candidates and the ratio of the number of planned recruits to the interviewees announced in the recruitment announcement, the list of the first batch of candidates who participated in the interview and professional ability test was determined in the order of passing the written test scores and the scores of qualified personnel in the qualification review from high to low. The list is scheduled to be published on January 12, 2024 on the general platform of personnel examination in Beijing.

  Third, adjust

  (a) announced the list of transfer positions and personnel.

  The first batch of recruitment positions in which the candidates who participated in the interview did not reach the interview proportion announced in the recruitment announcement are transfer positions, and the interview candidates will be supplemented by transfer. The list of transfer positions and qualified personnel will be published on January 12, 2024 on the general platform of personnel examination in Beijing.

  (two) the principles and conditions of transfer registration.

  1. The written test scores of candidates who apply for adjustment shall reach the qualified score line of the position to be adjusted;

  2. Candidates who apply for transfer shall meet the qualifications and requirements stipulated in the transfer position;

  3. Candidates who participate in the transfer can only apply for one transfer position;

  4. Candidates who have entered the first interview list are not allowed to participate in the transfer.

  (3) Transfer registration

  Transfer registration time is from 9:00 on January 15th to 18:00 on January 16th, 2024, and online registration is adopted. Candidates can log on to the general platform of Beijing Personnel Examination through their username and password at the time of registration, and fill in the relevant information of applying for adjustment. Candidates need to consult the information such as major, education, degree, qualifications and remarks required for the transfer position, please contact the recruitment agency directly. Before the end of the time for submitting the transfer application, candidates can re-select the position to apply for transfer.

  Candidates can print the Registration Form for the Transfer of Civil Servants in the 2024 Annual Examination of Beijing Organs at All Levels after 18:00 on January 16, 2024.

  (4) Qualification examination of swap.

  The qualification examination time for transfer is from 9:00 on January 17th to 18:00 on January 18th, 2024. On January 17, 2024, the municipal recruitment agencies and district-level civil servants’ administrative departments will notify the registered candidates to participate in the adjustment qualification examination by telephone according to the number of vacant positions, and the registered candidates will enter the adjustment qualification examination at the same time when they exceed the number of vacant positions due to the same written test results.

  The materials and related matters needing attention to be provided for the qualification examination of transfer are consistent with the qualification examination. After the number of qualified people in the qualification examination of transfer reaches the specified number of transfers, the municipal recruitment agencies and district-level civil servant departments will no longer conduct qualification examination of other candidates.

  (five) to determine the list of swap candidates.

  After the qualification examination of transfer, the municipal recruitment agencies and district-level civil servant departments will determine the list of transfer candidates according to the number of vacant positions and the grades from high to low. The list of transfer candidates will be announced on January 19, 2024 on the general platform of personnel examination in Beijing.

  Fourth, the interview and professional ability test

  The interview time is from February 28 to March 3, 2024, and the professional ability test time is determined by the recruitment agency. Please pay attention to the website of the recruitment agency for the specific time schedule.

  The interview work is organized by the municipal recruitment agencies and the district-level civil servant departments in accordance with the Measures for the Administration of Civil Servant Recruitment Interview Organization (Trial). For positions where the ratio of the number of individuals participating in the interview to the number of employment plans is less than 3:1, the interview scores of the interviewers should reach the average score of all the people interviewed by their interview examiner group using the same set of interview questions or the interview qualified score line determined by the recruitment agency in the interview announcement before entering the medical examination and inspection.

  After the interview and professional ability test, the candidates for medical examination and inspection will be determined in the order of high comprehensive scores.

Beijing Municipal Bureau of Civil Service

January 5, 2024

Starting from RMB 175,800, 2024 Jetway X95 will be launched! How strong is the product?

Recently, Jetway’s new car, the 2024 Jetway X95, went on the market! Positioning as a medium-sized SUV, two models have been launched, with the price range of 175,800-178,800 yuan. The new car is an annual model. What is the product strength? Take a closer look!

First of all, in terms of appearance, the new car adopts a family-style design language. The front face is a polygonal air intake grille, and the interior is filled with a blackened honeycomb structure. With the headlights on both sides, the internal structure is clearly visible, which is very eye-catching after lighting. The lower enclosure is a three-stage design, with diversion grooves on both sides and an air inlet in the middle, all of which are blackened and have a strong sporty atmosphere.

The luggage rack is designed on the side of the car body and the roof to increase practicality. The suspended roof, with segmented waistline, plus five-piece wheels, further enhances the sports attributes. The lower edge of the window is inlaid with chrome trim strips, which is more delicate. The inner concave treatment is carried out under the door, which makes it more layered. In terms of body size, the length, width and height of the new car are respectively4858/1925/1780mm, with a wheelbase of 2850mm.

At the rear of the car, the roof is designed with a duckling tail, which is matched with a spoiler and a high-position brake light, which is more sporty. The taillights are of split design, and the internal structure is clearly visible, which is very eye-catching after lighting. The license plate area is slightly concave, which is more layered. The rear enclosure is wrapped in a black plaque, which is full of movement with the diffuser shape. In terms of exhaust, the design of two outlets is adopted.

In terms of interior, the central control adopts a dual screen composed of full LCD instrument and central control screen, which is full of science and technology. Coupled with the three-position steering wheel and shifting mechanism, the driving atmosphere is good. In terms of material, a large number of leather materials are used to wrap, combined with exquisite stitching, and the texture is comfortable.

In terms of configuration,19-inch rims are standard.laneDeviation warning, tire pressure display, front/rear parking radar, reversing image, 360-degree panoramic image, cruise control, automatic parking, driving mode selection, openable panoramic sunroof, roof rack, 12.3-inch LCD instrument, keyless entry, wireless charging of mobile phone,Leather seat, 12.3-inch central control panel, LED far and near lightLights, automatic headlights,Automatic anti-glare interior rearview mirror, air outlet of rear air conditioner, manual air conditioner, etc.

In terms of power, the new car is equipped with a 1.6T turbocharged engine with a maximum power of 145 kW and a maximum torque of 290 Nm. In terms of transmission, it is matched with 7 speeds.Wet dual clutch gearbox.

On the whole, the appearance of the new car is fashionable and dynamic, the interior technology is online, coupled with the configuration and power, the product is remarkable. Considering the price, what do you think of this car? Welcome to leave a comment!

Roewe RX5 in Qingdao is offering a discount of 28,000 yuan! There are plenty of cars.

[car home Qingdao Preferential Promotion Channel] At present, large-scale preferential activities are being launched in Qingdao, with the maximum preferential amount reaching 28,000 yuan, which reduces the minimum starting price to 74,900 yuan. For consumers who plan to buy Roewe RX5, this is undoubtedly an excellent time to buy a car. In order to get more preferential information, please click "Check the car price" in the quotation form and strive for a higher discount.

青岛地区荣威RX5正在优惠,优惠2.8万!现车充足

Roewe RX5 adopts a fashionable and dynamic design. The front face is equipped with a large chrome grille and sharp LED headlights, which makes the whole vehicle look more dynamic. The body lines are smooth and muscular, creating a perfect combination of strength and movement. On the whole, the Roewe RX5 is exquisitely designed and highly recognizable.

青岛地区荣威RX5正在优惠,优惠2.8万!现车充足

Roewe RX5 has a length of 4655mm, a width of 1890mm and a height of 1664mm, and its wheelbase is 2765mm, providing spacious interior space for passengers. The side lines of the car body are smooth, with the front tread of 1590mm and the rear tread of 1584mm, which ensures the stability and handling of the vehicle. Equipped with 18-inch rims, tyre size is 215/60 R18, showing a dynamic and fashionable style.

青岛地区荣威RX5正在优惠,优惠2.8万!现车充足

The interior design of Roewe RX5 is mainly simple and atmospheric, creating a fashionable and technological atmosphere. The center console is equipped with a 12.3-inch central control screen, which supports the voice recognition control of multimedia system, navigation, telephone, air conditioner and skylight, and is easy to operate. The steering wheel is made of leather material, which feels comfortable and supports manual up and down+front and rear adjustment to meet the operating needs of different drivers. The seat is made of imitation leather. The main driver’s seat can be adjusted fore and aft, backrest and height. The co-pilot seat has the functions of fore and aft adjustment and backrest adjustment. The rear seat supports proportional reclining, which increases space flexibility. There are also multiple USB/Type-C interfaces in the car, which is convenient for charging.

青岛地区荣威RX5正在优惠,优惠2.8万!现车充足

Roewe RX5 is equipped with a 1.5T engine with a maximum power of 138kW (about 188HP) and a maximum torque of 300Nm. It is equipped with a 7-speed wet dual-clutch gearbox, which provides a strong power output and excellent acceleration performance for the vehicle.

According to the evaluation, the front face design of Roewe RX5 is very domineering, especially the large and thick X-shaped grille and sharp headlights on both sides, plus the slender light strip running through the tail and the segmented spoiler, which makes the vehicle look very three-dimensional and fashionable. In addition, the 20-inch super-large aluminum alloy wheels and hidden door handles also show the design concept of Roewe RX5 keeping up with the trend, which left a deep impression on the whole.

Consumer investment "two prosperous" sports industry trillion cakes to be divided

  What is "internet plus"? How does it affect our life step by step? Simply put, "internet plus" is the combination of traditional industries and the Internet. Relying on advanced Internet technology, Internet platform and Internet industry chain, various traditional industries have deeply integrated the Internet with traditional industries and created new economic forms. Worldwide, internet plus has set off an upsurge of upgrading traditional industries.

  In this upsurge, both large and medium-sized enterprises and small and micro enterprises are gearing up for transformation. When all enterprises are seeking transformation, relying on their unique resources, platforms and user advantages, large enterprises can often quickly connect with the Internet in a very short time. For example, Intime Department Store teamed up with Alibaba to build an online payment platform; Midea and Xiaomi married and launched intelligent induction air conditioning.

  Faced with the transformation of large and medium-sized enterprises, some small and micro enterprises began to become anxious. The transformation of large enterprises is either a platform, a system or an industrial chain. They have rich resources, huge user groups and detailed data … which small and micro enterprises do not have. Without a platform, data, users, resources and internet marketing technology, how can small and micro enterprises transform?

  Fortunately, the opportunities that the Internet brings to everyone are equal. Make good use of Internet technology to make the Internet the source of its own power, and every enterprise in the development of the Internet industry has the opportunity to achieve itself on the Internet.

  This book is different from the previous books about "internet plus". There is no lofty theory or unreachable routine. It is all about concrete, operable and ready-to-use strategies for internet plus’s transformation.

  In this book, I summed up my many years of working experience and practical experience in guiding small and medium-sized enterprises all over the country, and discussed in detail how small and micro enterprises can achieve themselves with "internet plus", and how small and micro enterprises and entrepreneurial enterprises can survive in the cracks when all walks of life are carrying out "internet plus".

  Under the current situation, there are many entrepreneurial enterprises at home and abroad, with a large base. Faced with the opportunities brought about by the vigorous development of the Internet, many young people want to join in and break out of their own world.

  Then, in the Internet age, young people want to start a business and small and micro enterprises want to develop. How should they do their own Internet marketing? In fact, as long as we make good use of some artifacts on the Internet, both individual entrepreneurs and small and micro enterprises can achieve good development.

  Liu Pengfei, a young man born in 1980s from a poor mountainous area, discovered a business opportunity by an unexpected opportunity-selling Kongming lanterns. Kongming Lantern has a simple structure and almost no technical content. Liu Pengfei can do it himself.

  After getting the salary of 1,400 yuan in the first month, Liu Pengfei fired his boss "Squid", and used 400 yuan to buy more than 100 Kongming lanterns to start e-commerce.

  Through online inquiry, Liu Pengfei found that no one sold Kongming Lantern on Alibaba and China-made platforms, but there were merchants abroad searching for Kongming Lantern through Google search engine. Liu Pengfei thought it was an opportunity and began to make great efforts to produce Kongming lanterns. At this stage, Liu Pengfei found the first bucket of gold in his life.

  In 2008, the number of manufacturers of Kongming lanterns in China increased sharply, and the competition was fierce. The major manufacturers started a price war. Liu Pengfei realized that Kongming Lantern must be promoted to the international market. As a result, Liu Pengfei introduced the "Flying China Lantern" to the world through Alibaba’s export link and Google search engine.

  In August, 2008, Liu Pengfei accepted the order of 1.5 million Kongming lanterns from the third largest German retailer. He expanded the scale of the enterprise, which made the enterprise’s benefits grow by leaps and bounds again and again, and realized the soaring 400 yuan to 70 million yuan.

  It doesn’t matter if you don’t have a platform, just use the existing platform. Without its own platform, Liu Pengfei, a young man born in 1980s, can still succeed in starting a business, which gives us profound enlightenment. In the Internet age, as long as you are good at using all available Internet resources around you, you can also succeed in starting a business.

  What are the most available resources around us for small and micro enterprises and some individual entrepreneurs? Mobile apps such as WeChat and Weibo are indispensable in people’s daily life.

  The pace of modern life is accelerating, and mobile phones have become an important part of people’s daily life. As long as we can make a fuss about customers’ mobile phones, we can attract customers to the maximum extent and complete the perfect connection between enterprises and the Internet.

  How to make good use of existing resources to do a good job in internet plus marketing? We must master four modes and four stages of fan marketing.

  What are the four marketing models in internet plus? It is a fan mode, a free mode, a mobile Internet mode and a self-media mode. None of these four modes requires enterprises to invest too much manpower and material resources, but the effect is obvious. For example, the sliding screen unlocking software means that by cutting into the user’s mobile phone, the mobile phone user can download other APP applications through sliding screen unlocking, and can get corresponding benefits, which greatly mobilizes the user’s enthusiasm for participation.

  What are the four stages of fan marketing in internet plus? We often say "no fans, no marketing". In the Internet age, if you want to keep your fans, you need to do these four stages: First, get your circle of friends; Second, learn to run your own WeChat official account; Third, you must have your own APP;; Fourth, establish your own ecological circle.

  Through gradual deepening and upgrading step by step, every start-up enterprise or individual can master the essence of internet plus, make internet plus’s theory and routines work for me, and do well in the Internet field.

Biden made a slip of the tongue in an interview by saying the wrong name of the president during the Great Depression (photo)


Biden, who has rich experience, also got the president’s name wrong during the Great Depression.


  Beijing, Sept. 24 (Xinhua)-In the current US general election, from the primary election of the two major parties to the current campaign, it seems that it has become a common occurrence for candidates or candidates to make slips of the tongue, say the wrong words or quote wrong data. Biden, the Democratic vice presidential candidate, made a mistake in the name of the American president in the Great Depression when he was interviewed by a TV station recently and expressed his views on the recent financial tsunami.


  According to Sing Tao Global Network, Biden said in an interview with the CBS evening news program that the leaders of today’s generation should learn from history books and learn from the late American President Roosevelt how to respond to the financial crisis.


  Biden said: "Do you know? When the stock market crashed, Roosevelt went on TV, not only complaining about how greedy others were. He said,’ Look! This is happening now!’ "


  However, looking up the history books, when the American stock market plunged in October 1929, which opened the curtain for the Great Depression, the president was not Roosevelt who belonged to the Democratic Party, but Hoover who belonged to the Republican Party. Roosevelt was elected to the White House three years later, that is, in the election year of 1932, and Hoover failed in his re-election. During his campaign, Roosevelt promised to take new actions to lead the country out of economic difficulties.


  It seems that Democrats often want to deliberately remind the public and voters that when the stock market crash triggered the Great Depression in 1929, the Republican Party was in charge. In the election year of 2004, the then Democratic candidate Kerry also repeatedly used Hoover as a topic, saying that he was the president who witnessed the shrinking employment position during his last term of office, followed by Bush.


  Commenting on the recent stock market crash, Biden said that leaders of today’s generation should explain to the public the current economic crisis and how to solve it. He pointed out: "As a leader, what you should do is to slowly restore the public’s confidence, show that they know what happened, and communicate with the public to explain how to solve the problem."


  This is not the first time that this presidential candidate or primary candidate has said something wrong. I remember that during the Democratic primary election, Hillary Clinton, a female senator from New York, once boasted and recalled the scene of bullets at the airport when she arrived in Bosnia by plane, but the reporter looked at the news clips and there was no such thing at all.

Editor: Meng Xu

The back row can be used as a bed! Large space and safe! XC90!

Throughout this year’s car market changes, in order to survive the economic winter, many brands have shown real "sincerity", Volvo is the same, among which (| |) has realized the car dream of many people at a very sincere price, and has also received quite gratifying feedback. In a single month alone, the car series has won the positive volume of the car series forum of 1271 owners in the Autohome forum. The number of car series fans has reached more than 570,000, and the high popularity has made Volvo XC90 famous. If you want to buy a car, the editor also recommends that you visit the car forum and listen to the voice of the real owner, which can make your car selection experience easier.

Autohome

In terms of appearance, the 2021 B6 Zhiya Deluxe Edition 7-seat car has smooth body lines, coordinated proportions, comfortable and durable. The size of the whole car is 4953mm, 1958mm, 1776mm, with 7 seats, and the trunk has reached a volume of 302-1856L, which can fully satisfy daily household use. The wheelbase has reached 2984mm, and it is matched with 275/45 R20 tires, which guarantees both passability and comfort. The exterior colors include flash silver gray, denim blue, agate black, pine forest gray, birch silver, crystal white, sea rock gray, and the interior also has black, black/beige, black/brown, black/gray. You can choose what color you like.

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In terms of multimedia configuration, the 2021 B6 Zhiya Deluxe Edition is equipped with a 9-inch central control LCD screen in 7 seats. The multimedia system equipped with this model is responsive and fully functional, which can meet the various functional needs of drivers and passengers. Its car stereo also uses the industry-famous Bowers & Wilkins Baohua Weijian audio, which has excellent sound fidelity, allowing drivers and passengers to enjoy a theatrical auditory feast while sitting in the car. A total of 19 speakers are arranged in the car, which greatly enhances the effect of music surround. In addition, common basic multimedia configurations such as Bluetooth/car phone, mobile phone interconnection/mapping are also arranged for everyone.

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In terms of space, 4953mm, 1958mm, 1776mm body length, width and height are matched with 2984mm wheelbase size, 7-seat design and 302-1856L luggage compartment volume, which is no problem for daily household use. In addition, the front main seat is equipped with backrest adjustment + height adjustment (4 directions) + waist support (4 directions) + front and rear adjustment + leg support adjustment adjustment method and the secondary seat is equipped with height adjustment (4 directions) + waist support (4 directions) + leg support adjustment + backrest adjustment + front and rear adjustment adjustment method, which is also more flexible for the control of space.

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In terms of safety, the car is equipped with main/passenger seat airbags, front/rear side airbags, front/rear head airbags (air curtain), knee airbags, tire pressure monitoring function, seat belt not wearing reminder, ISOFIX child seat interface, ABS anti-lock, braking force distribution (EBD/CBC, etc.), brake assist (EBA/BAS/BA, etc.), traction control (ASR/TCS/TRC, etc.), body stability control (ESC/ESP/DSC, etc.), parallel assist, lane departure warning system, lane keeping assist system, road traffic sign recognition, active braking/active safety system, fatigue driving prompts, so that the driver’s driving safety has been protected accordingly, although there is a safety configuration to provide blessing, but in the driving process We must remain vigilant at all times.

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In terms of power, the 2021 B6 Zhiya Deluxe Edition 7-seat is equipped with a 2.0l mechanical + turbocharged engine, with a maximum horsepower of 300Ps and a maximum power speed of 5400rpm, which is still good for models of the same class. On the other hand, the official 100-kilometer acceleration of the 2021 B6 Zhiya Deluxe Edition 7-seat is 6.7s, which is brisk and does not drag water.

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After reading the introduction of the Volvo XC90, how do you feel? Anyway, it is better to drive it in person and feel it. You can easily book a test drive by clicking the [Get Reserve Price] button. The end point can reach a price discount of up to 130,000 yuan, you can not miss it~

Recommended 390T two-wheel drive Xingyao version, Xingtu Lanyue car purchase guide

The Xingtu brand, which debuted at the 2017 Frankfurt Motor Show, can be regarded as a new force in the autonomous high-end field. It has three models: LX, TX and TXL, covering the mainstream compact SUV and medium-sized SUV segments. In order to achieve further upward breakthroughs in the brand and cater to its own high-end positioning, Xingtu planned a medium and large SUV model VX very early, but due to various reasons, the release time has been repeatedly delayed, which has whetted consumers’ appetite. Finally, the new car is determined to be officially launched on March 18, 2021, and the Chinese name Lanyue has been announced.

As the fourth SUV model launched by the Xingtu brand, Lanyue is no longer named with simple English letters, indicating that the new car will have a unique positioning. Due to the largest size in the Xingtu brand, and the use of exclusive M3X architecture and a large number of advanced technologies, Lanyue undoubtedly plays the role of family flagship. The listing of Xingtu Lanyue launched a total of 6 models, respectively equipped with the group’s latest 1.6T and 2.0T turbocharged engines, priced at 16.89-22 9,900 yuan. For a high-end mid-to-large SUV, consumers will definitely value its comprehensive configuration performance when purchasing, so which of the 6 models is more cost-effective?

Brief description of the model

Lanyue is based on the latest M3X Mars architecture of the Xingtu brand. Compared with previous products, Lanyue has a comprehensive improvement in safety and technology. Of course, as a family flagship model, Lanyue also shows a good temperament.

The appearance of Lanyue restores the design of the Xingtu VX concept car to the greatest extent, and the overall shape is slightly tough and full of futuristic atmosphere. The front face is more square, and the inside of the polygonal air intake grille is decorated with banner chrome, with large-sized headlights on both sides, which is full of momentum. The trapezoidal lower grille is wrapped in silver chrome decoration, and the fog lamp area on both sides also adds vent decoration, which looks more youthful and fashionable.

The side has the stable temperament of a medium and large SUV, and the straight waist line and wide eyebrows show a certain sense of strength. The tail shape is relatively heavy, and the through-type LED taillights play a finishing touch to the overall design. The reflector design on both sides echoes the fog lights on the front of the car. The bottom silver lower guard and chrome-plated double tail row add a sporty atmosphere.

The Lanyue series offers two sizes of rims, among which the entry-level Star Enjoy Edition and the three Star Yao Edition models are all in the 19-inch double five-spoke Y shape, and they are painted in black, which is full of sports. The tires are made of Magis Victra Sport 5 series products, which focus on sports and handling. The tire specifications are 235/55 R19; while the high-end Star Rui version and Star Zun version are equipped with 20-inch two-tone multi-spoke rims, which has a stronger design sense. The tires are made of Continental MaxContact MC6 series products, which have excellent safety and comfort. The tire specifications are 245/45 R20.

In terms of appearance color, Lanyue offers 5 body colors to choose from, namely meteorite gray, star track blue, Haoyue white, nebula purple, and phantom night black. The main color is star track blue, which shows a stable temperament without losing a sense of fashion. Haoyue white and phantom night black two colors are biased towards the style, while meteorite gray and nebula purple are obviously more personalized.

The interior design of Lanyue generally continues the family design style. The regular layout and a large number of horizontal lines effectively stretch the visual width. The full LCD instrument and central control screen use the mainstream dual-screen floating design, which has a strong sense of technology. In addition, as a high-end brand, Lanyue is also more particular about the materials used. The center console, front and rear door panels and other parts have added dark wood grain decoration, and the seats are also made of Meridian punched leather with diamond-shaped pattern design, creating a more luxurious atmosphere.

In terms of configuration, all Lanyue models come standard with full LED headlights, headlight height adjustment, keyless entry/start and other functions. In terms of multimedia, it is equipped with Lion4.0 Lion Zhiyun system, which supports FOTA cloud upgrade, remote start, GPS real-time car navigation, smart home interconnection, mobile phone interconnection/mapping Apple CarPlay and other functions. The high-end models are also equipped with L2.5-level automatic driving assistance system, including ACC adaptive cruise, FCW front collision warning, LKA lane keeping, TJA traffic congestion assistance and other functions.

In terms of power, Lanyue is equipped with the latest third-generation ACTECO engine, providing 1.6TGDI and 2.0TGDI engines, with maximum power of 197 horsepower and 254 horsepower respectively, and peak torque of 290 Nm and 390 Nm respectively. The transmission system is matched with a 7-speed wet dual-clutch gearbox and is equipped with a timely four-wheel drive system.

II. Vehicle configuration highlights and recommendations

The 290T two-wheel drive Star Enjoy Edition is an entry-level model for the whole series of Lanyue, priced at 168,900 yuan. Although the price is advantageous for a mid-to-large SUV positioned at the high end, a closer look at the configuration sheet shows that there are not many bright spots, which only meet the basic needs. First, the entry-level model is equipped with a 1.6TGDI engine. Although the maximum power is not much different from the 2.0TGDI version, the maximum torque is still 100 Nm apart. Secondly, in terms of frequently used lights and auxiliary driving functions, the entry-level model is only equipped with LED near and far lights, and does not provide the two practical functions of automatic headlights and adaptive near and far lights, which are currently more popular. In addition, the entry-level model only provides the rear radar and ordinary reversing image functions, and the lack of front radar and 360-degree panoramic images may affect driving or parking at narrow intersections. In terms of active and passive safety, the configuration performance of the entry-level model is not comprehensive enough. Not only is it not equipped with the L2.5 level automatic driving assistance system promoted by the manufacturer, but even the airbag only provides the front and side four configurations, and lacks the protection of the head airbag. In addition, in terms of seat configuration, the performance of the entry-level model is also quite decent. The seat is made of ordinary leather material, only the main driver’s seat is electrically adjusted, and it is not equipped with a practical waist support adjustment function, which greatly reduces the ride comfort. Of course, the entry-level model’s configuration performance in multimedia and air conditioning is still worthy of recognition. The whole system is equipped with a 12.3-inch central control display, and the commonly used navigation, automatic speech recognition, mobile phone interconnection, vehicle to everything and OTA upgrades are also readily available. Air conditioners are equipped with three-zone automatic air conditioners as standard in the whole system, and the rear row also provides a separate trend and control area. Considering the low power and configuration of the entry-level model, combined with its relatively affordable price, it is only suitable for consumers who have a small budget and do not have high requirements for power and configuration.

III. Difference analysis of recommended vehicle configurations

As a low-end model, the 290T two-wheel drive Xingyao version priced at 179,900 yuan is 10,000 yuan more expensive than the entry-level model. The added configuration mainly focuses on convenience and comfort, including front radar and 360-degree panoramic images, electric trunk with induction function, leather seats, lumbar support adjustment, front seat heating, driver’s seat memory, etc., which greatly improves the car experience. At the same time, the model has also been slightly upgraded for lighting multimedia, adding functions such as automatic headlights, facial recognition and the original driving recorder. But from the configuration and price point of view, the cost performance of this model is still OK. If you don’t care about the lack of 1.6TGDI engine power, then the 290T two-wheel drive Xingyao version is a good choice.

Compared with the two 290T models, the four 390T models not only have better power performance, but also have a higher overall configuration level. Especially in terms of active safety and lighting, the 390T models are equipped with L2.5-level automatic driving assistance systems, including ACC adaptive cruise, FCW front collision warning, LKA lane keeping, TJA traffic congestion assistance and other functions. In addition, the 390T models are also equipped with adaptive far and near light to improve night driving safety.

Among the four 390T models, the editor’s key recommendation is the 390T two-wheel drive Xingyao version priced at 188,900 yuan. On the basis of the configuration of the 290T two-wheel drive Xingyao version, in addition to adding the L2.5 level automatic driving assistance system, the HUD head-up display and adaptive far and near light functions are also added to further improve safety. Although some configurations are also reduced accordingly, such as front radar, front mobile phone wireless charging, waist support adjustment, etc., it has little impact on daily car use, and the value of the increased configuration is much higher than the reduced configuration, and the comprehensive cost performance is higher.

The overall configuration of the 390T four-wheel drive version is very close to the recommended model, the difference is only that it is equipped with a timely four-wheel drive system, and the price has also increased by 12,000 yuan. Considering that the timely four-wheel drive system has limited improvement in the actual performance of the vehicle, and the fuel consumption of the four-wheel drive model is relatively higher, if the car environment is mainly urban roads, then the 390T four-wheel drive version is also not recommended. As for the two high-end models, on the one hand, the price is relatively high, and on the other hand, the added configuration plays a more icing on the cake role. Including parallel assist, reversing car side warning, seat ventilation, 8-speaker SONY audio, steering assist light, exterior rearview mirror memory, exterior rearview mirror reversing automatic down, automatic anti-glare interior rearview mirror, negative ion generator, etc. These configurations can certainly enhance the luxury temperament of the vehicle, but they are not very helpful for daily use. Therefore, from the perspective of comprehensive price and various configurations, the 390T two-wheel drive Xingyao version has a more obvious cost-effective advantage among all models of Xingtu Lanyue, and it is recommended to give priority when purchasing.

Hanzhong Haval second generation big dog is on sale! The latest offer 122,800, quantity is limited

[Autohome Hanzhong Discount Promotion Channel] Special report, there is a big promotion going on in Hanzhong area. Car buyers are in for a treat, because this popular SUV is currently offering up to 13,000 yuan in cash. The starting price is already as low as 122,800 yuan, which is very attractive. If you want to seize this wave of car buying opportunities, be sure to click "Chatti Car Price" in the quotation form to get the best car buying conditions. This is a rare opportunity, don’t miss it!

汉中哈弗二代大狗特价出售!最新报价12.28万,数量有限

The Haval II Big Dog impresses with its unique exterior design. The front face adopts the latest design concept of the Haval family, with a highly recognizable large-size air intake grille and rough lines, showing strength and wildness. The overall style of the body blends elements of hard off-road and urban leisure, which not only meets the needs of urban drivers, but also meets the spirit of outdoor adventure. The streamlined body line is combined with large-size tires to further strengthen its off-road performance and practicality. Whether it is the front face or the overall shape, the Haval II Big Dog reflects the ingenuity of the Haval brand and the precise grasp of consumer needs.

汉中哈弗二代大狗特价出售!最新报价12.28万,数量有限

With its well-designed side lines, the Haval II Big Dog presents a solid body profile. Its body dimensions reach 4705mm long, 1908mm wide, and an elegant height of 1780mm, with a wheelbase of 2810mm, providing a solid foundation for interior space and driving stability. The front and rear wheel tracks are 1641mm and 1640mm respectively, ensuring a good driving balance. The tire size is 235/60 R19, and it is paired with a sporty wheel rim design, which not only enhances the driving performance, but also adds a stylish atmosphere to the vehicle. Overall, the side design of the Haval II Big Dog balances power and aesthetics, providing a pleasing visual experience for the driver.

汉中哈弗二代大狗特价出售!最新报价12.28万,数量有限

The interior design of Haval’s second-generation big dog highlights the style of both refinement and practicality. In the spacious cockpit, the steering wheel is made of high-quality leather materials, which not only provides a comfortable grip, but also supports manual up and down + front and rear adjustment to adapt to the individual needs of the driver. The 14.6-inch central control screen stands in the center, with clear display and convenient operation. It integrates multimedia systems, navigation, telephone and other functions to bring passengers an intelligent driving experience.

In terms of seats, the car is made of imitation leather and genuine leather to provide good ride comfort. The main driver’s seat has 4-way height adjustment, front and rear adjustment and waist support adjustment, with heating and ventilation functions, and is also equipped with electric memory function, which is convenient for the driver to adjust to the ideal position at any time. The passenger seat also supports front and rear adjustment and backrest adjustment to meet the needs of different passengers.

The wireless charging function of mobile phones is located in the front row, which brings convenience to modern life. The second row of seats supports backrest adjustment, and the space layout is flexible and changeable, while the proportional rear seats provide rich loading space to meet the needs of diverse life scenarios. Overall, the interior design of Haval’s second-generation big dog takes into account functionality and luxury, creating a warm and comfortable interior environment for passengers.

汉中哈弗二代大狗特价出售!最新报价12.28万,数量有限

Haval’s second-generation Big Dog is equipped with a 1.5T turbocharged engine with a maximum power of 135 kilowatts, providing the vehicle with surging power. This engine drives the vehicle with 184 horsepower, ensuring strong acceleration and driving stability. With a 7-speed wet dual-clutch transmission, it can achieve a smooth shift experience, enhancing driving pleasure while also taking into account fuel economy.

Overall, the Autohome owner’s evaluation of the Haval II big dog is multi-faceted. He particularly emphasizes the upgrade of the exterior design, considering it a major highlight, although some people have different opinions. In terms of power performance, the standard mode has satisfied him, and the potential of the sports mode is expected to be explored in the future experience. The spacious space, especially the rear comfort, allows the owner to enjoy the driving pleasure to the fullest. Although the trunk is slightly compact, the functional configuration such as 360-degree imaging and practical functions such as automatic parking undoubtedly increase the driving safety. Overall, the owner’s overall satisfaction with the Haval II big dog is real.